SERPINA7
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Full Name
Serpin Family A Member 7
Function
Major thyroid hormone transport protein in serum.
Biological Process
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process thyroid hormone transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process thyroid hormone transportManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Secreted
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Anti-SERPINA7 antibodies
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CompareTarget: SERPINA7
Host: Mouse
Specificity: Human
Clone: CBXS-2528
Application*: E, F, IC, IH, WB
Target: SERPINA7
Host: Mouse
Specificity: Human
Clone: CBXS-2527
Application*: E, WB
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1966
Application*: WB
Target: SERPINA7
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-1156
Application*: E, WB
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1099
Application*: E
Target: SERPINA7
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-1046
Application*: E
Target: SERPINA7
Host: Mouse
Specificity: Human
Clone: CBXS-0232
Application*: WB, IC, P, C, E
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C3H11
Application*: WB, E
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4246
Application*: E
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3860
Application*: E, WB
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5730
Application*: WB, F, E, IH, IF, MC
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBYJT-1670
Application*: E, WB
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-1667
Application*: E
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1666
Application*: WB
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1665
Application*: E
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3576
Application*: WB
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4504
Application*: IH, IC, F
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0566
Application*: SE
Target: SERPINA7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0565
Application*: SE
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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