SERPINB4
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.
Full Name
serpin family B member 4
Function
May act as a protease inhibitor to modulate the host immune response against tumor cells.
Biological Process
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of peptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protection from natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of proteolysis1 PublicationNAS:UniProtKB
Biological Process negative regulation of peptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protection from natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of proteolysis1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm
Seems to also be secreted in plasma by cancerous cells but at a low level.
Seems to also be secreted in plasma by cancerous cells but at a low level.
View more
Anti-SERPINB4 antibodies
+ Filters
Loading...
CompareTarget: SERPINB4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1047
Application*: P
Target: SERPINB4
Host: Mouse
Specificity: Human
Clone: CBXS-0240
Application*: WB, IC, P, C, E
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0239
Application*: E, WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0238
Application*: E, WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5564
Application*: WB, IH, IF
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5078
Application*: WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5007
Application*: WB, IH, P
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4998
Application*: P, WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4659
Application*: WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4571
Application*: E, WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4418
Application*: WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4179
Application*: WB
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5925
Application*: E
Target: SERPINB4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5621
Application*: E, WB
More Infomation
Hot products 
-
Mouse Anti-CEMIP Recombinant Antibody (3C12) (CBMAB-K0296-LY)
-
Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007) (CBMAB-Z0012-WJ)
-
Mouse Anti-ACE2 Recombinant Antibody (V2-179293) (CBMAB-A0566-YC)
-
Mouse Anti-BRCA2 Recombinant Antibody (CBYY-1728) (CBMAB-2077-YY)
-
Mouse Anti-CDK7 Recombinant Antibody (CBYY-C1783) (CBMAB-C3221-YY)
-
Mouse Anti-AHCYL1 Recombinant Antibody (V2-180270) (CBMAB-A1703-YC)
-
Mouse Anti-ELAVL4 Recombinant Antibody (6B9) (CBMAB-1132-YC)
-
Mouse Anti-AMOT Recombinant Antibody (CBYC-A564) (CBMAB-A2552-YC)
-
Mouse Anti-COL12A1 Recombinant Antibody (CBYY-C3117) (CBMAB-C4560-YY)
-
Rat Anti-ADGRE4 Recombinant Antibody (V2-160163) (CBMAB-F0011-CQ)
-
Mouse Anti-AK4 Recombinant Antibody (V2-180419) (CBMAB-A1891-YC)
-
Rabbit Anti-BAD (Phospho-Ser136) Recombinant Antibody (CAP219) (CBMAB-AP536LY)
-
Mouse Anti-CARD11 Recombinant Antibody (CBFYC-0811) (CBMAB-C0866-FY)
-
Rat Anti-CD63 Recombinant Antibody (7G4.2E8) (CBMAB-C8725-LY)
-
Mouse Anti-ADAM29 Recombinant Antibody (V2-179787) (CBMAB-A1149-YC)
-
Mouse Anti-CD33 Recombinant Antibody (P67.6) (CBMAB-C10189-LY)
-
Mouse Anti-CAPZB Recombinant Antibody (CBYY-C0944) (CBMAB-C2381-YY)
-
Mouse Anti-BACE1 Recombinant Antibody (61-3E7) (CBMAB-1183-CN)
-
Mouse Anti-CD2AP Recombinant Antibody (BR083) (CBMAB-BR083LY)
-
Mouse Anti-F11R Recombinant Antibody (402) (CBMAB-0026-WJ)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry
