Mouse Anti-SERPINB4 Recombinant Antibody (CBXS-0238) (CBMAB-S3215-CQ)

Name: Mouse Anti-SERPINB4 Recombinant Antibody (CBXS-0238)
SKU: CBMAB-S3215-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-0238

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

Citrate-Tris-HCl, pH 7.0

Preservative

0.02% Proclin 300

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

serpin family B member 4

Introduction

The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.

Entrez Gene ID

6318

UniProt ID

P48594

Alternative Names

LEUPIN; PI11; SCCA-2; SCCA1; SCCA2

Function

May act as a protease inhibitor to modulate the host immune response against tumor cells.

Biological Process

Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of peptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protection from natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of proteolysis1 PublicationNAS:UniProtKB

Cellular Location

Cytoplasm
Seems to also be secreted in plasma by cancerous cells but at a low level.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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