SYNDIG1
This gene encodes a protein that belongs to the interferon-induced transmembrane family of proteins. A similar protein in rat is thought to regulate the development of excitatory synapses.
Full Name
Synapse Differentiation Inducing 1
Function
May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.
Biological Process
Biological Process intracellular protein transportISS:UniProtKB
Biological Process positive regulation of synapse assemblyIDA:UniProtKB1 Publication
Biological Process synaptic vesicle clusteringISS:UniProtKB
Biological Process positive regulation of synapse assemblyIDA:UniProtKB1 Publication
Biological Process synaptic vesicle clusteringISS:UniProtKB
Cellular Location
Cell membrane
Early endosome membrane
Postsynaptic density membrane
Synapse
Cell projection, dendrite
Cell projection, dendritic spine
Shuttles between the cell surface and early endosome membrane.
Early endosome membrane
Postsynaptic density membrane
Synapse
Cell projection, dendrite
Cell projection, dendritic spine
Shuttles between the cell surface and early endosome membrane.
Topology
Cytoplasmic: 1-181
Helical: 182-202
Extracellular: 203-228
Helical: 229-249
Extracellular: 250-258
Helical: 182-202
Extracellular: 203-228
Helical: 229-249
Extracellular: 250-258
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Anti-SYNDIG1 antibodies
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Target: SYNDIG1
Host: Mouse
Specificity: Human
Clone: CBXS-2079
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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