TNFSF8

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Full Name
TNFSF8 Gene(Protein Coding) TNF Superfamily Member 8
Function
Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Biological Process
Biological Process CD8-positive, alpha-beta T cell differentiation Source:GO_Central1 Publication
Biological Process cell-cell signaling Source:ProtInc1 Publication
Biological Process defense response to Gram-positive bacterium Source:Ensembl
Biological Process immune response Source:InterPro
Biological Process positive regulation of transcription by RNA polymerase II Source:Ensembl
Biological Process regulation of T cell proliferation Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Cytoplasmic: 1-37
Helical: 38-62
Extracellular: 63-234
View more

Anti-TNFSF8 antibodies

+ Filters
Loading...

Mouse Anti-TNFSF8 Recombinant Antibody (4C6) (CBMAB-A9389-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C6
Application*: E, E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (4A9) (CBMAB-A9388-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4A9
Application*: E, E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (4A6) (CBMAB-A9387-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4A6
Application*: E, E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (4A10) (CBMAB-A9386-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4A10
Application*: WB, E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (3G9) (CBMAB-A9385-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3G9
Application*: WB, E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (4E6) (CBMAB-A9384-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4E6
Application*: WB, E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (4E4) (CBMAB-A9383-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4E4
Application*: WB, E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (4E3) (CBMAB-A9382-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4E3
Application*: WB, E
Datasheet SDS

Rat Anti-TNFSF8 Recombinant Antibody (RM0353-9C33) (CBMAB-C12604-LY)

Go to compareCompare
Target: TNFSF8
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0353-9C33
Application*: WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (MM0168-3G56) (CBMAB-C12603-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: MM0168-3G56
Application*: WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (2E11) (CBMAB-C13586-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: 2E11
Application*: E, WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (CBYY-C1190) (CBMAB-C2627-YY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-C1190
Application*: WB
Datasheet SDS

Rat Anti-TNFSF8 Recombinant Antibody (82414) (CBMAB-C8957-LY)

Go to compareCompare
Target: TNFSF8
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 82414
Application*: WB, EC
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (3G56) (CBMAB-C6161-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 3G56
Application*: WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (116615) (CBMAB-C2466-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 116615
Application*: WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (116614) (CBMAB-C0215-LY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 116614
Application*: F, N, MC
Functional Assay
Datasheet SDS

TNFSF8 Matched Antibody Pair (1247) (APMAB-1247LY)

Go to compareCompare
Target: TNFSF8
Specificity: Human
Datasheet SDS

Rat Anti-TNFSF8 Recombinant Antibody (RM153) (CBMAB-C2063-CQ)

Go to compareCompare
Target: TNFSF8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: RM153
Application*: F
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (CBXC-0956) (CBMAB-C1218-CQ)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-0956
Application*: F
Datasheet SDS

Rat Anti-Tnfsf8 Recombinant Antibody (CBYJT-4014) (CBMAB-T3427-YJ)

Go to compareCompare
Target: Tnfsf8
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-4014
Application*: F, IH, FN, IP
Datasheet SDS

Rat Anti-Tnfsf8 Recombinant Antibody (CBYJT-4012) (CBMAB-T3425-YJ)

Go to compareCompare
Target: Tnfsf8
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJT-4012
Application*: WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (CBYJT-4008) (CBMAB-T3421-YJ)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4008
Application*: E, WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (CBYJT-4007) (CBMAB-T3420-YJ)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4007
Application*: E
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (CBYJT-4002) (CBMAB-T3415-YJ)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4002
Application*: E, WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (CBYJT-4001) (CBMAB-T3414-YJ)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYJT-4001
Application*: WB
Datasheet SDS

Mouse Anti-TNFSF8 Recombinant Antibody (CBFYC-3193) (CBMAB-C3270-FY)

Go to compareCompare
Target: TNFSF8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-3193
Application*: F, N
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry