Sign in or Register   Sign in or Register
  |  

Mouse Anti-ATRIP Recombinant Antibody (EG315) (CBMAB-EN346-LY)

The product is antibody recognizes ATRIP (Phospho-Ser68) . The antibody EG315 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:40000.
See all ATRIP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
EG315
Antibody Isotype
IgG1
Application
WB, IP, IF

Basic Information

Immunogen
The immunogen used to generate this antibody corresponds to human ATRIP.
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500-1:3,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 20% Glycerol
Preservative
None
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
ATR Interacting Protein
Introduction
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Entrez Gene ID
Human84126
Mouse235610
Rat301014
UniProt ID
HumanQ8WXE1
MouseQ8BMG1
RatD4A4M3
Alternative Names
ATR Interacting Protein; ATM And Rad3-Related-Interacting Protein; AGS1;
Function
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Biological Process
DNA damage checkpoint Source: GO_Central
DNA repair Source: GO_Central
DNA replication Source: Reactome
Interstrand cross-link repair Source: Reactome
Regulation of signal transduction by p53 class mediator Source: Reactome
Cellular Location
Nucleus. Redistributes to discrete nuclear foci upon DNA damage.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ATRIP Recombinant Antibody (EG315)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare