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Mouse Anti-DYRK4 Recombinant Antibody (3B9) (CBMAB-D2032-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dual Specificity Tyrosine Phosphorylation Regulated Kinase 4 (DYRK4). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all DYRK4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3B9
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
DYRK4 (AAH31244, 421 a.a. ~ 520 a.a) partial recombinant protein with GST tag. The immunogen sequence: FFPSETRKDK VQGCHHSSRK ADEITKETTE KTKDSPTKHV QHSGDQQDCL QHGADTVQLP QLVDAPKKSE AAVGAEVSMT SPGQSKNFSL KNTNVLPPIV
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 421-520

Target

Full Name
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
Introduction
DYRK4 is an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Entrez Gene ID
8798
UniProt ID
Q9NR20
Alternative Names
Dual Specificity Tyrosine Phosphorylation Regulated Kinase 4; EC 2.7.12.1; Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 4; Dual Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 4; EC 2.7.12;
Research Area
Possible non-essential role in spermiogenesis.
Biological Process
Peptidyl-serine phosphorylation Source: GO_Central
Peptidyl-threonine phosphorylation Source: GO_Central
Cellular Location
Isoform 1: Cytoplasm
Isoform 2: Cytoplasm; Nucleus.
PTM
Autophosphorylation on Tyr-264 in the activation loop is required for kinase activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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