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Mouse Anti-GRHPR Recombinant Antibody (10A3) (CBMAB-G4850-LY)

This product is antibody recognizes GRHPR. The antibody 10A3 immunoassay techniques such as: FC.
See all GRHPR antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
10A3
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
GRHPR antibody was raised in mouse using a full length recombinant protein of human GRHPR (NP_036335) produced in HEK293T cells, as the immunogen
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol,1% BSA
Preservative
0.02% sodium azide
Concentration
0.5 mg-1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glyoxylate And Hydroxypyruvate Reductase
Introduction
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
9380
UniProt ID
Q9UBQ7
Alternative Names
Glyoxylate And Hydroxypyruvate Reductase; Glyoxylate Reductase And Hydroxypyruvate Reductase; Glyoxylate Reductase/Hydroxypyruvate Reductase; GLXR; Primary Hyperoxaluria Type 2; Glycerate-2-Dehydrogenase;
Function
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
Biological Process
Carboxylic acid metabolic process Source: Reactome
Dicarboxylic acid metabolic process Source: Ensembl
Excretion Source: UniProtKB
Glyoxylate metabolic process Source: UniProtKB
Cellular Location
Cytosol; Extracellular exosome; Peroxisomal matrix; Catalytic complex; Cytoplasm
Involvement in disease
Hyperoxaluria primary 2 (HP2):
A disorder characterized by elevated urinary excretion of oxalate and L-glycerate, progressive tissue accumulation of insoluble calcium oxalate, nephrolithiasis, nephrocalcinosis, and end-stage renal disease.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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