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Mouse Anti-LGMN Recombinant Antibody (M1) (CBMAB-A4943-LY)

The product is antibody recognizes LGMN. The antibody M1 immunoassay techniques such as: sELISA, ELISA.
Host Species
Mouse
Application
sELISA, ELISA
Immunogen
LGMN (AAH03061.1, 1 a.a. ~ 433 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG1, κ
Specificity
Human
Clone
M1
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq]
Alternative Name
AEP; LGMN1; PRSC1
Entrez Gene ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-A4943-LY
Conjugates
Size
Price $
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Second antibody and isotype control