Mouse Anti-MBIP Recombinant Antibody (CBFYM-1806) (CBMAB-M1974-FY)

This product is mouse antibody that recognizes MBIP. The antibody CBFYM-1806 can be used for immunoassay techniques such as: Dot.
See all MBIP antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-1806

Antibody Isotype

IgG1

Application

Dot

Basic Information

Immunogen

Recombinant Human Map3 K12 Binding Inhibitory Protein 1 (Mbip)

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

0.1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MAP3K12 Binding Inhibitory Protein 1

Introduction

MBIP is a Protein Coding gene. Among its related pathways are Chromatin organization. Gene Ontology annotations related to this gene include identical protein binding and protein kinase inhibitor activity.

Entrez Gene ID

51562

UniProt ID

Q9NS73

Alternative Names

MAP3K12 Binding Inhibitory Protein 1; MAPK Upstream Kinase-Binding Inhibitory Protein; MUK-Binding Inhibitory Protein

Function

Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

Biological Process

Histone H3 acetylation Source: BHF-UCL
Histone H3-K14 acetylation Source: ComplexPortal
Positive regulation of gene expression Source: GO_Central
Positive regulation of JNK cascade Source: GO_Central
Regulation of cell cycle Source: ComplexPortal
Regulation of cell division Source: ComplexPortal
Regulation of embryonic development Source: ComplexPortal
Regulation of histone deacetylation Source: ComplexPortal
Regulation of transcription, DNA-templated Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: ComplexPortal
Regulation of tubulin deacetylation Source: ComplexPortal

Cellular Location

Nucleus
Cytoplasm and Cytosol
Note: Shows a cytoplasmic localization when coexpressed with MAP3K12.

References

Ma, Y., Hua, Y., Yin, X. J., Jiao, Y., Xu, E., Yan, T., ... & Zhang, L. (2024). MBIP promotes ESCC metastasis by activating MAPK pathway. Cellular Signalling, 111040.

Yanchun, M., Yuyan, H., Ye, J., Enwei, X., Ting, Y., Jian, Y., & Ling, Z. (2023). MBIP promotes ESCC metastasis by activating MAPK pathway.

Ochieng, J. K., Kundu, S. T., Bajaj, R., Leticia Rodriguez, B., Fradette, J. J., & Gibbons, D. L. (2020). MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs. Oncogene, 39(43), 6719-6732.

Shareefi, G., Turkistani, A. N., Alsayyah, A., Kussaibi, H., Had, M. A., & Alkharsah, K. R. (2020). Pathway-affecting single nucleotide polymorphisms (SNPs) in RPS6KA1 and MBIP genes are associated with breast cancer risk. Asian Pacific Journal of Cancer Prevention: APJCP, 21(7), 2163.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-MBIP Recombinant Antibody (CBFYM-1806)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-MBIP Recombinant Antibody (A1020)

Mouse Anti-MBIP Recombinant Antibody (CBFYM-1805)

Mouse Anti-MBIP Recombinant Antibody (2E2)

Mouse Anti-MBIP (AA 1-344) Recombinant Antibody (CBFYM-1807)

Mouse Anti-MBIP Recombinant Antibody (CBFYM-0586)

Mouse Anti-MBIP Recombinant Antibody (CF280)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: