MBIP
MBIP (MAP3K12 Binding Inhibitory Protein 1) is a Protein Coding gene. Among its related pathways are Chromatin organization. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein kinase inhibitor activity.
Full Name
MAP3K12 Binding Inhibitory Protein 1
Function
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Biological Process
Histone H3 acetylation Source: BHF-UCL
Histone H3-K14 acetylation Source: ComplexPortal
Positive regulation of gene expression Source: GO_Central
Positive regulation of JNK cascade Source: GO_Central
Regulation of cell cycle Source: ComplexPortal
Regulation of cell division Source: ComplexPortal
Regulation of embryonic development Source: ComplexPortal
Regulation of histone deacetylation Source: ComplexPortal
Regulation of transcription, DNA-templated Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: ComplexPortal
Regulation of tubulin deacetylation Source: ComplexPortal
Histone H3-K14 acetylation Source: ComplexPortal
Positive regulation of gene expression Source: GO_Central
Positive regulation of JNK cascade Source: GO_Central
Regulation of cell cycle Source: ComplexPortal
Regulation of cell division Source: ComplexPortal
Regulation of embryonic development Source: ComplexPortal
Regulation of histone deacetylation Source: ComplexPortal
Regulation of transcription, DNA-templated Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: ComplexPortal
Regulation of tubulin deacetylation Source: ComplexPortal
Cellular Location
Nucleus
Cytoplasm and Cytosol
Note: Shows a cytoplasmic localization when coexpressed with MAP3K12.
Cytoplasm and Cytosol
Note: Shows a cytoplasmic localization when coexpressed with MAP3K12.
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Anti-MBIP antibodies
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Target: MBIP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF280
Application*: ELISA, WB, IHC, IP
Target: MBIP
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E2
Application*: IF, E
Target: MBIP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: A1020
Application*: ELISA, IHC, WB
Target: MBIP
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-1807
Application*: E, IC, IF
Target: MBIP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-1806
Application*: DB
Target: MBIP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-1805
Application*: E, WB, IH, IP
Target: MBIP
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-0586
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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