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MBIP

MBIP (MAP3K12 Binding Inhibitory Protein 1) is a Protein Coding gene. Among its related pathways are Chromatin organization. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein kinase inhibitor activity.

Full Name

MAP3K12 Binding Inhibitory Protein 1

Function

Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

Biological Process

Histone H3 acetylation Source: BHF-UCL
Histone H3-K14 acetylation Source: ComplexPortal
Positive regulation of gene expression Source: GO_Central
Positive regulation of JNK cascade Source: GO_Central
Regulation of cell cycle Source: ComplexPortal
Regulation of cell division Source: ComplexPortal
Regulation of embryonic development Source: ComplexPortal
Regulation of histone deacetylation Source: ComplexPortal
Regulation of transcription, DNA-templated Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: ComplexPortal
Regulation of tubulin deacetylation Source: ComplexPortal

Cellular Location

Nucleus
Cytoplasm and Cytosol
Note: Shows a cytoplasmic localization when coexpressed with MAP3K12.

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Anti-MBIP antibodies

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Mouse Anti-MBIP Recombinant Antibody (CF280) (CBMAB-FT223LY)

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Target: MBIP

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CF280

Application*: ELISA, WB, IHC, IP

Mouse Anti-MBIP Recombinant Antibody (2E2) (CBMAB-A5332-LY)

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Target: MBIP

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2E2

Application*: IF, E

Mouse Anti-MBIP Recombinant Antibody (A1020) (CBMAB-AP11669LY)

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Target: MBIP

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: A1020

Application*: ELISA, IHC, WB

Mouse Anti-MBIP (AA 1-344) Recombinant Antibody (CBFYM-1807) (CBMAB-M1975-FY)

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Target: MBIP

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-1807

Application*: E, IC, IF

Mouse Anti-MBIP Recombinant Antibody (CBFYM-1806) (CBMAB-M1974-FY)

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Target: MBIP

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-1806

Application*: DB

Mouse Anti-MBIP Recombinant Antibody (CBFYM-1805) (CBMAB-M1973-FY)

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Target: MBIP

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYM-1805

Application*: E, WB, IH, IP

Mouse Anti-MBIP Recombinant Antibody (CBFYM-0586) (CBMAB-M0717-FY)

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Target: MBIP

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-0586

Application*: E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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