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Mouse Anti-PRMT3 Recombinant Antibody (3G4) (CBMAB-P2935-YC)

Provided herein is a Mouse monoclonal antibody against Human Protein Arginine Methyltransferase 3. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PRMT3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G4
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid in PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protein arginine methyltransferase 3
Introduction
PRMT3 belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome.
Entrez Gene ID
10196
UniProt ID
O60678
Alternative Names
HRMT1L3
Function
Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable). May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity (PubMed:33495566).
Biological Process
Dendritic spine morphogenesisIEA:Ensembl
Negative regulation of protein ubiquitinationManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of retinoic acid biosynthetic processManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-arginine methylation, to asymmetrical-dimethyl arginineIEA:Ensembl
Protein methylationTAS:Reactome
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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