PRMT3

Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 [PubMed 9642256]).[supplied by OMIM

Full Name

protein arginine methyltransferase 3

Function

Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable). May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity (PubMed:33495566).

Biological Process

Dendritic spine morphogenesisIEA:Ensembl
Negative regulation of protein ubiquitinationManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of retinoic acid biosynthetic processManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-arginine methylation, to asymmetrical-dimethyl arginineIEA:Ensembl
Protein methylationTAS:Reactome

Cellular Location

Cytoplasm

Anti-PRMT3 antibodies

Mouse Anti-PRMT3 Recombinant Antibody (CBYC-P639) (CBMAB-P2937-YC)

Datasheet

SDS

Target: PRMT3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYC-P639

Application*: IP

Mouse Anti-PRMT3 Recombinant Antibody (PRMT3-367) (CBMAB-P2936-YC)

Datasheet

SDS

Target: PRMT3

Host: Mouse

Antibody Isotype: IgG3

Specificity: Human, Mouse, Rat

Clone: PRMT3-367

Application*: E, IC, IF, WB

Mouse Anti-PRMT3 Recombinant Antibody (3G4) (CBMAB-P2935-YC)

Datasheet

SDS

Target: PRMT3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3G4

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)