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PRMT3

Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 [PubMed 9642256]).[supplied by OMIM

Full Name

protein arginine methyltransferase 3

Function

Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable). May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity (PubMed:33495566).

Biological Process

Dendritic spine morphogenesisIEA:Ensembl
Negative regulation of protein ubiquitinationManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of retinoic acid biosynthetic processManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-arginine methylation, to asymmetrical-dimethyl arginineIEA:Ensembl
Protein methylationTAS:Reactome

Cellular Location

Cytoplasm

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Anti-PRMT3 antibodies

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Mouse Anti-PRMT3 Recombinant Antibody (CBYC-P639) (CBMAB-P2937-YC)

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Target: PRMT3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYC-P639

Application*: IP

Mouse Anti-PRMT3 Recombinant Antibody (PRMT3-367) (CBMAB-P2936-YC)

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Target: PRMT3

Host: Mouse

Antibody Isotype: IgG3

Specificity: Human, Mouse, Rat

Clone: PRMT3-367

Application*: E, IC, IF, WB

Mouse Anti-PRMT3 Recombinant Antibody (3G4) (CBMAB-P2935-YC)

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Target: PRMT3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3G4

Application*: E, WB

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Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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