Mouse Anti-RHD Recombinant Antibody (3H2011) (CBMAB-R2507-CN)

Name: Mouse Anti-RHD Recombinant Antibody (3H2011)
SKU: CBMAB-R2507-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

3H2011

Application

FC, IP

Immunogen

Human erythrocytes

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

More Infomation

Target

Full Name

Rh Blood Group D Antigen

Introduction

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Entrez Gene ID

6007

UniProt ID

Q02161

Alternative Names

Rh Blood Group D Antigen; Rhesus D Antigen; RHXIII; RHPII; Rhesus Blood Group D Antigen Allele DIII Type 7; Truncated Rhesus Blood Group D Antigen; Truncated Rh Blood Group D Antigen; Rhesus Blood Group, D Antigen; Blood Group Rh(D) Polypeptide; Rh Blood Group Antigen Evans; Rh Blood Group CcEe Antigen; Rhesus System D Polypeptide; Rh Blood Group CE Antigen; Rh Blood Group, D Anitgen; Rh Blood Group C Antigen; RhD Blood Group Antigen; Blood Group Protein RHD; Blood Group Antigen D; Truncated Rhesus D; RH Polypeptide 2;

Function

May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.

Biological Process

Biological Process ammonium homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process ammonium transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Involvement in disease

Hemolytic disease of fetus and newborn, RH-induced (HDFNRH):
A disease that occurs in pregnancies in which mothers who lack the D antigen (RhD) of the Rh blood group have been exposed to the RhD-positive red cells of the fetus. The resulting maternal autoantibodies cross the placenta and destroy fetal red cells.

PTM

Palmitoylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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