Rabbit Anti-TINF2 Recombinant Antibody (
5G11) (V2LY-0725-LY1593)
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Positive WB detected in: RAW264.7 whole cell lysate, HL-60 whole cell lysate, Mouse Herat whole cell lysate, Mouse Brain whole cell lysate
All lanes: Tin2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 51, 40, 16 kDa
Observed band size: 51 kDa
Basic Information
| Application | Note |
| WB | 1:500-1:5,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Biological Process negative regulation of protein ADP-ribosylationSource:BHF-UCL1 Publication
Biological Process negative regulation of telomere maintenance via telomeraseSource:BHF-UCL1 Publication
Biological Process positive regulation of telomere maintenanceSource:ComplexPortal1 Publication
Biological Process protein localization to chromosome, telomeric regionSource:CACAO1 Publication
Biological Process regulation of telomere maintenance via telomere lengtheningSource:BHF-UCL1 Publication
Biological Process telomere assemblySource:BHF-UCL1 Publication
Biological Process telomere cappingSource:ComplexPortal1 Publication
Chromosome, telomere
Associated with telomeres.
Isoform 1
Nucleus matrix
A rare multisystem disorder caused by defective telomere maintenance. It is characterized by progressive bone marrow failure, and the clinical triad of reticulated skin hyperpigmentation, nail dystrophy, and mucosal leukoplakia. Common but variable features include premature graying, aplastic anemia, low platelets, osteoporosis, pulmonary fibrosis, and liver fibrosis among others. Early mortality is often associated with bone marrow failure, infections, fatal pulmonary complications, or malignancy.
Dyskeratosis congenita, autosomal dominant, 5 (DKCA5):
A disease characterized by bone marrow hypoplasia, nail dystrophy, fine sparse hair, fine reticulate skin pigmentation, oral leukoplakia, bilateral exudative retinopathy, cerebellar hypoplasia, and growth retardation.
5G11)?
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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