Mouse Anti-UPP1 Recombinant Antibody (2F5) (CBMAB-C4712-CN)

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Basic Information

Host Animal
Mouse
Clone
2F5
Application
ELISA, IHC, WB
Immunogen
Partial recombinant corresponding to aa 1-92 from human UPP1 (NP_003355) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
More Infomation

Target

Full Name
uridine phosphorylase 1
Introduction
This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]
Entrez Gene ID
UniProt ID
Alternative Names
Uridine Phosphorylase 1; UrdPase 1; UPase 1; UP; Uridine Phosphorylase; EC 2.4.2.3; UDRPASE; UPASE; UPP;
Function
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:7488099).
The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Biological Process
Biological Process cellular response to glucose starvation Source:Ensembl
Biological Process CMP catabolic process Source:Ensembl
Biological Process dCMP catabolic process Source:Ensembl
Biological Process dTMP catabolic process Source:Ensembl
Biological Process dUMP catabolic process Source:Ensembl
Biological Process nucleobase-containing compound metabolic process Source:ProtInc1 Publication
Biological Process UMP catabolic process Source:Ensembl
Biological Process UMP salvage Source:UniProtKB-UniPathway
Biological Process uridine catabolic process Source:UniProtKB1 Publication
Cellular Location
cytosol
nucleoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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