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Mouse Anti-UTS2 Recombinant Antibody (CBCNC-823) (CBMAB-C4782-CN)

This product is a Mouse antibody that recognizes UTS2. The antibody CBCNC-823 can be used for immunoassay techniques such as: WB, ICC, IHC-P, IHC-F, ELISA.
See all UTS2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNC-823
Application
WB, ICC, IHC-P, IHC-F, ELISA

Basic Information

Immunogen
Urotensin 2
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.02% Sodium azide

Target

Full Name
Urotensin 2
Introduction
This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
10911
UniProt ID
O95399
Alternative Names
Urotensin 2; Urotensin II; Prepro U-II; U-II; UII; Urotensin-2; PRO1068; UCN2;
Function
Highly potent vasoconstrictor.
Biological Process
Biological Process blood vessel diameter maintenance Source:Ensembl
Biological Process chemical synaptic transmission Source:ProtInc1 Publication
Biological Process muscle contraction Source:ProtInc1 Publication
Biological Process negative regulation of blood pressure Source:Ensembl
Biological Process negative regulation of glomerular filtration Source:Ensembl
Biological Process negative regulation of heart rate Source:Ensembl
Biological Process negative regulation of insulin secretion Source:Ensembl
Biological Process negative regulation of renal sodium excretion Source:Ensembl
Biological Process negative regulation of urine volume Source:Ensembl
Biological Process positive regulation of angiogenesis Source:Ensembl
Biological Process positive regulation of blood pressure Source:Ensembl
Biological Process positive regulation of cell differentiation Source:Ensembl
Biological Process positive regulation of circadian sleep/wake cycle, REM sleep Source:Ensembl
Biological Process positive regulation of circadian sleep/wake cycle, wakefulness Source:Ensembl
Biological Process positive regulation of collagen biosynthetic process Source:Ensembl
Biological Process positive regulation of cytosolic calcium ion concentration Source:Ensembl
Biological Process positive regulation of fibroblast migration Source:Ensembl
Biological Process positive regulation of fibroblast proliferation Source:Ensembl
Biological Process positive regulation of heart rate Source:Ensembl
Biological Process positive regulation of synaptic transmission, cholinergic Source:Ensembl
Biological Process regulation of blood pressure Source:GO_Central1 Publication
Biological Process response to hypoxia Source:Ensembl
Biological Process response to testosterone Source:Ensembl
Biological Process response to xenobiotic stimulus Source:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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