CAPG

CAPG (Capping Actin Protein, Gelsolin Like) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding and protein complex binding. An important paralog of this gene is GSN.

Full Name

Capping Actin Protein, Gelsolin Like

Function

Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.

Biological Process

Actin filament severing Source: GO_Central
Actin polymerization or depolymerization Source: GO_Central
Barbed-end actin filament capping Source: GO_Central
Cell projection assembly Source: GO_Central
Central nervous system development Source: GO_Central
Protein-containing complex assembly Source: ProtInc

Cellular Location

Nucleus; Cytoplasm; Melanosome; Lamellipodium; Ruffle. In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia.

PTM

The N-terminus is blocked.

Anti-CAPG antibodies

Mouse Anti-CAPG Recombinant Antibody (CBXC-2814) (CBMAB-C4972-CQ)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-2814

Application*: E, WB, IH, IF

Mouse Anti-CAPG (AA 1-348) Recombinant Antibody (CBFYC-0789) (CBMAB-C0844-FY)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse

Clone: CBFYC-0789

Application*: WB, F, E, IF

Mouse Anti-CAPG Recombinant Antibody (4E1) (CBMAB-AP767LY)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4E1

Application*: ELISA, IF, IHC, WB

Mouse Anti-CAPG Recombinant Antibody (CBLC084-LY) (CBMAB-C9685-LY)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBLC084-LY

Application*: SE, E, WB, IF

Mouse Anti-CAPG Recombinant Antibody (6D6) (CBMAB-C8221-LY)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 6D6

Application*: E, IF, WB

Mouse Anti-CAPG Recombinant Antibody (1F1) (CBMAB-C3999-LY)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1F1

Application*: E, IF, WB

Mouse Anti-CAPG Recombinant Antibody (1D10) (CBMAB-C0496-LY)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse

Clone: 1D10

Application*: WB, F, E, IC/IF

Mouse Anti-CAPG Recombinant Antibody (CBYC-A928) (CBMAB-A4274-YC)

Datasheet

SDS

Target: CAPG

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYC-A928

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)