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CD1d

CD1D (CD1d Molecule) is a Protein Coding gene. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include receptor activity and cell adhesion molecule binding. An important paralog of this gene is CD1E.

Full Name

CD1d Molecule

Function

Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.

Biological Process

Antigen processing and presentation, endogenous lipid antigen via MHC class Ib Source: UniProtKB
Antigen processing and presentation, exogenous lipid antigen via MHC class Ib Source: GO_Central
Detection of bacterium Source: UniProtKB
Heterotypic cell-cell adhesion Source: BHF-UCL
Innate immune response Source: UniProtKB-KW
Positive regulation of innate immune response Source: UniProtKB
Positive regulation of T cell mediated cytotoxicity Source: GO_Central
Positive regulation of T cell proliferation Source: BHF-UCL
Regulation of immune response Source: Reactome
T cell selection Source: UniProtKB

Cellular Location

Lysosome membrane; Endoplasmic reticulum membrane; Endosome membrane; Cell membrane; Basolateral cell membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.

Topology

Extracellular: 20-301
Helical: 302-322
Cytoplasmic: 323-335

Anti-CD1d antibodies

Mouse Anti-CD1D Recombinant Antibody (CBXC-0185) (CBMAB-C4500-CQ)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-0185

Application*: IH, IP, WB

Mouse Anti-CD1D Recombinant Antibody (CBXC-0184) (CBMAB-C4499-CQ)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-0184

Application*: IF, IH, IP, WB

Mouse Anti-CD1D Recombinant Antibody (CBFYC-1137) (CBMAB-C1195-FY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-1137

Application*: E, WB, IH, siRNA

Rat Anti-CD1D Recombinant Antibody (20H2/HB-323) (CBMAB-C4357-LY)

SDS

Target: CD1D

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse

Clone: 20H2/HB-323

Application*: B, F, IP

Rat Anti-CD1D Recombinant Antibody (A036) (CBMAB-AP11989LY)

SDS

Target: CD1D

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: A036

Application*: ELISA

Mouse Anti-CD1D Recombinant Antibody (997) (CBMAB-AP982LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 997

Application*: ELISA, IHC, WB

Mouse Anti-CD1D Recombinant Antibody (WTH2) (CBMAB-C10050-LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Rat, Mouse

Clone: WTH2

Application*: F

Mouse Anti-CD1D Recombinant Antibody (WTH1) (CBMAB-C10049-LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Mouse, Rat

Clone: WTH1

Application*: WB, IP, E, C, FN, F

Mouse Anti-CD1D Recombinant Antibody (9L89) (CBMAB-C1590-CN)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 9L89

Application*: IH, IP

Mouse Anti-CD1D Recombinant Antibody (CBYY-C1219) (CBMAB-C2656-YY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYY-C1219

Application*: WB

Rat Anti-CD1D Recombinant Antibody (CBYY-C1217) (CBMAB-C2654-YY)

SDS

Target: CD1D

Host: Rat

Antibody Isotype: IgM, κ

Specificity: Mouse

Clone: CBYY-C1217

Application*: F

Rat Anti-CD1D Recombinant Antibody (1B1) (CBMAB-C0475-LY)

SDS

Target: CD1D

Host: Rat

Antibody Isotype: IgG2b, κ

Specificity: Mouse

Clone: 1B1

Application*: C, FN, IH, IP

Mouse Anti-CD1D Recombinant Antibody (703335) (CBMAB-C8406-LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 703335

Application*: WB

Mouse Anti-CD1D Recombinant Antibody (3H649) (CBMAB-C6338-LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3H649

Application*: IF, IH, IP, WB

Mouse Anti-CD1D Recombinant Antibody (1C12F1) (CBMAB-C3717-LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1C12F1

Application*: E, WB, IH

Mouse Anti-CD1D Recombinant Antibody (51-1) (CBMAB-C2683-LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 51-1

Application*: F, C, P

Mouse Anti-CD1D Recombinant Antibody (51.1) (CBMAB-C2657-LY)

SDS

Target: CD1D

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 51.1

Application*: F, C, IP

Rat Anti-CD1d Recombinant Antibody (19G11) (CBMAB-0972-LY)

SDS

Target: CD1d

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: 19G11

Application*: N

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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