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CD1d

CD1D (CD1d Molecule) is a Protein Coding gene. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include receptor activity and cell adhesion molecule binding. An important paralog of this gene is CD1E.
Full Name
CD1d Molecule
Alternative Names
CD1d Molecule; CD1D Antigen, D Polypeptide; CD1d Antigen; R3G1; HMC Class I Antigen-Like Glycoprotein CD1D; Antigen-Presenting Glycoprotein CD1d;
Function
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
Biological Process
Antigen processing and presentation, endogenous lipid antigen via MHC class Ib Source: UniProtKB
Antigen processing and presentation, exogenous lipid antigen via MHC class Ib Source: GO_Central
Detection of bacterium Source: UniProtKB
Heterotypic cell-cell adhesion Source: BHF-UCL
Innate immune response Source: UniProtKB-KW
Positive regulation of innate immune response Source: UniProtKB
Positive regulation of T cell mediated cytotoxicity Source: GO_Central
Positive regulation of T cell proliferation Source: BHF-UCL
Regulation of immune response Source: Reactome
T cell selection Source: UniProtKB
Cellular Location
Lysosome membrane; Endoplasmic reticulum membrane; Endosome membrane; Cell membrane; Basolateral cell membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Topology
Extracellular: 20-301
Helical: 302-322
Cytoplasmic: 323-335
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Anti-CD1d antibodies

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Mouse Anti-CD1D Recombinant Antibody (C1590) (CBMAB-C1590-CN)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: C1590
Application*: IF, E, IP, WB
Datasheet SDS

Mouse Anti-CD1d Recombinant Antibody (AG08) (V2LY-0524-LY85)

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Target: CD1d
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: AG08
Application*: In Vivo, IP, WB
In Vivo Assay
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (CBT3153) (V2LY-0625-LY1672)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT3153
Application*: F
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (C3D5) (CBMAB-C10050-LY)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: C3D5
Application*: IF, P, IP, WB
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (NOR3.2) (CBMAB-C10049-LY)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: NOR3.2
Application*: IF, P, IP, WB
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (CBXC-0185) (CBMAB-C4500-CQ)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0185
Application*: IF, E, IP, WB
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (CBXC-0184) (CBMAB-C4499-CQ)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: CBXC-0184
Application*: IF, E, IP, WB
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (CBYY-C1219) (CBMAB-C2656-YY)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1219
Application*: E, WB, IH
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (CBFYC-1137) (CBMAB-C1195-FY)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1137
Application*: E, WB, F
Datasheet SDS

Rat Anti-CD1D Recombinant Antibody (1B1) (CBMAB-C0475-LY)

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Target: CD1D
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 1B1
Application*: F, IP, IH
Datasheet SDS

Mouse Anti-CD1D Recombinant Antibody (3H649) (CBMAB-C6338-LY)

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Target: CD1D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H649
Application*: IF, P, IP, WB
Datasheet SDS

Rat Anti-CD1d Recombinant Antibody (19G11) (CBMAB-0972-LY)

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Target: CD1d
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 19G11
Application*: N, in vivo
In Vivo Assay Functional Assay
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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