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FAAH

This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide. [provided by RefSeq, Jul 2008]
Full Name
Fatty Acid Amide Hydrolase
Research Area
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules (PubMed:9122178, PubMed:17015445, PubMed:19926788).

Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (PubMed:9122178, PubMed:17015445).

It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol) (PubMed:21049984).

FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids (By similarity).
Biological Process
Arachidonic acid metabolic process Source: Reactome
Fatty acid catabolic process Source: UniProtKB
Monoacylglycerol catabolic process Source: UniProtKB
Cellular Location
Cytoskeleton; Endomembrane system. Seems to be attached to intracellular membranes and a portion of the cytoskeletal network.
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Anti-FAAH antibodies

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Mouse Anti-FAAH Recombinant Antibody (5F9) (CBMAB-A2790-LY)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 5F9
Application*: WB, E
Datasheet SDS

Mouse Anti-FAAH Recombinant Antibody (2C3) (CBMAB-A2784-LY)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: 2C3
Application*: WB, E
Datasheet SDS

Rabbit Anti-FAAH Recombinant Antibody (CBXF-2786) (CBMAB-F3499-CQ)

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Target: FAAH
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXF-2786
Application*: P, WB
Datasheet SDS

Rabbit Anti-FAAH Recombinant Antibody (CBXF-2050) (CBMAB-F2008-CQ)

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Target: FAAH
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXF-2050
Application*: WB, IH
Datasheet SDS

Mouse Anti-FAAH Recombinant Antibody (CBXF-0217) (CBMAB-F0777-CQ)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-0217
Application*: WB, E, IP
Datasheet SDS

Mouse Anti-FAAH Recombinant Antibody (CBXF-2785) (V2LY-0825-LY1183)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-2785
Application*: E, WB
Datasheet SDS

Mouse Anti-FAAH Recombinant Antibody (CBXF-2784) (V2LY-0825-LY1182)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-2784
Application*: E, WB
Datasheet SDS

Mouse Anti-FAAH Recombinant Antibody (CBXF-0218) (V2LY-0825-LY1181)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0218
Application*: E, WB
Datasheet SDS

Mouse Anti-FAAH Recombinant Antibody (CBXF-2221) (V2LY-0825-LY1180)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBXF-2221
Application*: E, WB
Datasheet SDS

Mouse Anti-FAAH Recombinant Antibody (CBXF-0216) (V2LY-0825-LY1177)

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Target: FAAH
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0216
Application*: WB, IF
Datasheet SDS

FAAH Matched Antibody Pair (397) (APMAB-397LY)

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Target: FAAH
Specificity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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