FCRL5

This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Full Name
Fc Receptor Like 5
Alternative Names
Fc Receptor Like 5; Immune Receptor Translocation-Associated Protein 2; Fc Receptor Homolog 5; FcR-Like Protein 5; BXMAS1; FCRH5; IRTA2; Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2);
Research Area
May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Involvement in disease
A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32).
Topology
Extracellular: 16-851
Helical: 852-872
Cytoplasmic: 873-977
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Anti-FCRL5 antibodies

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Mouse Anti-FcRL5 Recombinant Antibody (AG72) (V2LY-0524-LY23)

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Target: FcRL5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: AG72
Application*: B, F, In Vivo, IP
In Vivo Assay Functional Assay
Datasheet SDS

Rabbit Anti-FCRL5 Recombinant Antibody (EG1186) (CBMAB-EN1429-LY)

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Target: FCRL5
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1186
Application*: WB: 1:500~1:1000 ELISA: 1:10000
Datasheet SDS

Mouse Anti-FCRL5 Recombinant Antibody (CBT4473) (V2LY-0625-LY1221)

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Target: FCRL5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4473
Application*: F
Datasheet SDS

Mouse Anti-FCRL5 Recombinant Antibody (CBT4587) (V2LY-0625-LY1192)

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Target: FCRL5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4587
Application*: IC, F
Datasheet SDS

Human Anti-FCRL5 Recombinant Antibody (CBXC-0837) (CBMAB-C1951-CQ)

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Target: FCRL5
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0837
Application*: F
Datasheet SDS

Mouse Anti-FCRL5 Recombinant Antibody (CBYY-C0306) (CBMAB-C1033-YY)

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Target: FCRL5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C0306
Application*: F, IP
Datasheet SDS

Mouse Anti-FCRL5 Recombinant Antibody (CBXF-2937) (CBMAB-F3644-CQ)

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Target: FCRL5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2937
Application*: F
Datasheet SDS

Mouse Anti-FCRL5 Recombinant Antibody (CBXF-2596) (CBMAB-F3029-CQ)

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Target: FCRL5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2596
Application*: WB
Datasheet SDS

Mouse Anti-FCRL5 (AA 16-844) Recombinant Antibody (CBXF-0483) (CBMAB-F2296-CQ)

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Target: FCRL5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0483
Application*: E, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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