Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-FCRL5 Recombinant Antibody (CBT4587) (V2LY-0625-LY1192)


See all FCRL5 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4587
Antibody Isotype
IgG1
Application
ICC, FC

Basic Information

Immunogen
Purified recombinant fragment of human CD307E (AA: extra 16-158) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ICC1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Fc Receptor Like 5
Entrez Gene ID
83416
UniProt ID
Q96RD9
Alternative Names
Fc Receptor Like 5; Immune Receptor Translocation-Associated Protein 2; Fc Receptor Homolog 5; FcR-Like Protein 5; BXMAS1; FCRH5; IRTA2; Immunoglobulin Superfamily Receptor Translocation Associated 2 (IRTA2);
Research Area
May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Involvement in disease
A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32).
Topology
Extracellular: 16-851
Helical: 852-872
Cytoplasmic: 873-977
More Infomation

Ogega, C. O., Skinner, N. E., Flyak, A. I., Clark, K. E., Board, N. L., Bjorkman, P. J., ... & Bailey, J. R. (2022). B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection. PLoS pathogens, 18(1), e1010179.

Reyes, R. A., Clarke, K., Gonzales, S. J., Cantwell, A. M., Garza, R., Catano, G., ... & Bunnik, E. M. (2021). SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease. PloS one, 16(12), e0261656.

Gonzales, S. J., Bol, S., Braddom, A. E., Sullivan, R., Reyes, R. A., Ssewanyana, I., ... & Bunnik, E. M. (2021). Longitudinal analysis of FcRL5 expression and clonal relationships among classical and atypical memory B cells following malaria. Malaria journal, 20(1), 1-15.

Liu, H. W., Wei, D. X., He, D. W., Deng, J. Z., Zhu, J. J., Xu, K., ... & Fu, L. G. (2020). The rs6427384 and rs6692977 Single Nucleotide Polymorphisms of the Fc Receptor-Like 5 (FCRL5) Gene and the Risk of Ankylosing Spondylitis: A Case Control Study in a Single Center in China. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 26, e920956-1.

Gu, Z., Shen, Y., Tang, X. Y., Ke, X., Yao, H. B., Hong, S. L., & Kang, H. Y. (2019). Genetic risk of FCRL3 and FCRL5 polymorphisms in children with asthma and allergic rhinitis in a Chinese Han population. International journal of pediatric otorhinolaryngology, 120, 58-63.

Franco, A., Kraus, Z., Li, H., Seibert, N., Dement-Brown, J., & Tolnay, M. (2018). CD21 and FCRL5 form a receptor complex with robust B-cell activating capacity. International immunology, 30(12), 569-578.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-FCRL5 Recombinant Antibody (CBT4587)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry