HK3

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.

Full Name

Hexokinase 3

Function

Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:8717435).

Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:8717435).

Biological Process

Canonical glycolysis Source: Reactome
Cellular glucose homeostasis Source: GO_Central
Fructose 6-phosphate metabolic process Source: UniProtKB
Glucose 6-phosphate metabolic process Source: UniProtKB
Glycolytic process Source: GO_Central

Cellular Location

Cytosol; Extracellular region; Mitochondrion; Ficolin-1-rich granule lumen; Secretory granule lumen

Anti-HK3 antibodies

Mouse Anti-HK3 Recombinant Antibody (CBFYH-3583) (CBMAB-H4136-FY)

Datasheet

SDS

Target: HK3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Rat

Clone: CBFYH-3583

Application*: IH

Mouse Anti-HK3 Recombinant Antibody (CBFYH-1241) (CBMAB-H2213-FY)

Datasheet

SDS

Target: HK3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYH-1241

Application*: E, WB

Mouse Anti-HK3 Recombinant Antibody (CBFYH-1240) (CBMAB-H2212-FY)

Datasheet

SDS

Target: HK3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-1240

Application*: E, WB, P

Mouse Anti-HK3 (AA 1-923) Recombinant Antibody (CBFYH-1239) (CBMAB-H2211-FY)

Datasheet

SDS

Target: HK3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-1239

Application*: E, P, WB

Mouse Anti-HK3 (AA 1-923) Recombinant Antibody (CBFYH-1238) (CBMAB-H0514-FY)

Datasheet

SDS

Target: HK3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYH-1238

Application*: WB, F, E, IF

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)