NFIA

This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Full Name
nuclear factor I A
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Biological Process
DNA replicationIEA:UniProtKB-KW
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription, DNA-templated1 PublicationNAS:UniProtKB
Synapse maturationIEA:Ensembl
Ureter developmentIEA:Ensembl
Viral genome replication1 PublicationNAS:UniProtKB
Cellular Location
Nucleus
Involvement in disease
Brain malformations with or without urinary tract defects (BRMUTD):
A syndrome characterized by corpus callosum hypoplasia or agenesis, hydrocephalus or ventricular enlargement, developmental delay, and urinary tract defects.
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Anti-NFIA antibodies

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Mouse Anti-NFIA Antibody (2C6) (CBMAB-0722-YC)

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Target: NFIA
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 2C6
Application*: CI, IP, WB, M
Datasheet SDS

Mouse Anti-NFIA Antibody (2B12) (CBMAB-0721-YC)

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Target: NFIA
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 2B12
Application*: IP, WB, M
Datasheet SDS

Mouse Anti-NFIA Antibody (1B8) (CBMAB-0720-YC)

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Target: NFIA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1B8
Application*: IP, M
Datasheet SDS

Mouse Anti-NFIA Recombinant Antibody (16H11) (CBMAB-BR371LY)

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Target: NFIA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 16H11
Application*: FC, IHC-P, WB
Datasheet SDS

Mouse Anti-NFIA Recombinant Antibody (CBWJN-0390) (CBMAB-N0318-WJ)

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Target: NFIA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0390
Application*: DB, WB
Datasheet SDS

Mouse Anti-NFIA Recombinant Antibody (1E11) (CBMAB-N0317-WJ)

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Target: NFIA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E11
Application*: E, IF, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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