PRRX2

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq]
Full Name
PRRX2
Function
May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development.
Biological Process
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription, DNA-templated1 PublicationNAS:UniProtKB
Cellular Location
Nucleus
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Anti-PRRX2 antibodies

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PRRX2 Matched Antibody Pair (935) (APMAB-935LY)

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Target: PRRX2
Specificity: Human
Datasheet SDS

PRRX2 Matched Antibody Pair (934) (APMAB-934LY)

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Target: PRRX2
Specificity: Human
Datasheet SDS

Mouse Anti-PRRX2 Recombinant Antibody (R353.1.1G11) (CBMAB-P3052-YC)

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Target: PRRX2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: R353.1.1G11
Application*: IP
Datasheet SDS

Mouse Anti-PRRX2 Recombinant Antibody (4C9) (CBMAB-P3051-YC)

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Target: PRRX2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4C9
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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