SUMF2

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Full Name
sulfatase modifying factor 2
Function
Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1.
Cellular Location
Endoplasmic reticulum lumen
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Anti-SUMF2 antibodies

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Rat Anti-SUMF2 Recombinant Antibody (CBXS-3462) (CBMAB-S6193-CQ)

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Target: SUMF2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-3462
Application*: E, WB
Datasheet SDS

Mouse Anti-SUMF2 Recombinant Antibody (CBXS-3168) (CBMAB-S5910-CQ)

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Target: SUMF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-3168
Application*: E, WB
Datasheet SDS

Rat Anti-SUMF2 Recombinant Antibody (CBXS-1811) (CBMAB-S4622-CQ)

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Target: SUMF2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1811
Application*: WB
Datasheet SDS

Mouse Anti-SUMF2 Recombinant Antibody (CBXS-1777) (CBMAB-S4594-CQ)

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Target: SUMF2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1777
Application*: WB, IP
Datasheet SDS

Mouse Anti-SUMF2 (C-Term) Recombinant Antibody (CBXS-3691) (CBMAB-S0966-CQ)

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Target: SUMF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3691
Application*: E, C, P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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