Mouse Anti-APBB1IP Recombinant Antibody (CBT2297) (V2LY-0625-LY186)

Name: Mouse Anti-APBB1IP Recombinant Antibody (CBT2297)
SKU: V2LY-0625-LY186
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-APBB1IP Recombinant Antibody (CBT2297) (V2LY-0625-LY186) in WB

Mouse Anti-APBB1IP Recombinant Antibody (CBT2297) (V2LY-0625-LY186) in FC

Mouse Anti-APBB1IP Recombinant Antibody (CBT2297) (V2LY-0625-LY186) in ELISA

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBT2297

Application

Immunogen

Purified recombinant fragment of human APBB1IP (AA: 1-151) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
FC	1:200-1:400
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Amyloid Beta Precursor Protein Binding Family B Member 1 Interacting Protein

Entrez Gene ID

54518

UniProt ID

Q7Z5R6

Function

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.

Biological Process

Positive regulation of cell adhesion Source: Ensembl
Signal transduction Source: InterPro
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Cellular Location

Cytoskeleton; Cell membrane; Lamellipodium; Focal adhesion; Colocalizes with ENA/VASP proteins at lamellipodia tips and focal adhesions, and F-actin at the leading edge. At the membrane surface, associates, via the PH domain, preferentially with the inositol phosphates, PtdIns5P and PtdIns3P. This binding appears to be necessary for the efficient interaction of the RA domain to Ras-GTPases (By similarity).

Ge, Q., Li, G., Chen, J., Song, J., & Cai, G. (2021). Immunological Role and Prognostic Value of APBB1IP in Pan-Cancer Analysis. Journal of Cancer, 12(2), 595.

Ashbrook, D. G., Cahill, S., & Hager, R. (2019). A cross-species systems genetics analysis links APBB1IP as a candidate for schizophrenia and prepulse inhibition. Frontiers in behavioral neuroscience, 13, 266.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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