APBB1IP

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
Full Name
Amyloid Beta Precursor Protein Binding Family B Member 1 Interacting Protein
Function
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
Biological Process
Positive regulation of cell adhesion Source: Ensembl
Signal transduction Source: InterPro
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
Cellular Location
Cytoskeleton; Cell membrane; Lamellipodium; Focal adhesion; Colocalizes with ENA/VASP proteins at lamellipodia tips and focal adhesions, and F-actin at the leading edge. At the membrane surface, associates, via the PH domain, preferentially with the inositol phosphates, PtdIns5P and PtdIns3P. This binding appears to be necessary for the efficient interaction of the RA domain to Ras-GTPases (By similarity).
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Anti-APBB1IP antibodies

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Mouse Anti-APBB1IP Recombinant Antibody (CBT4621) (V2LY-0625-LY187)

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Target: APBB1IP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4621
Application*: IH, F
Datasheet SDS

Mouse Anti-APBB1IP Recombinant Antibody (CBT2297) (V2LY-0625-LY186)

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Target: APBB1IP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2297
Application*: F
Datasheet SDS

Mouse Anti-APBB1IP Recombinant Antibody (7E7D12) (CBMAB-1087-CN)

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Target: APBB1IP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E7D12
Application*: E, FC, WB, IH
Datasheet SDS

Mouse Anti-APBB1IP Recombinant Antibody (7E7A3) (CBMAB-1086-CN)

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Target: APBB1IP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E7A3
Application*: E, FC, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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