Mouse Anti-DTYMK Recombinant Antibody (1E6) (V2LY-0425-LY1041)

Name: Mouse Anti-DTYMK Recombinant Antibody (1E6)
SKU: V2LY-0425-LY1041
Rating: 5 (1 reviews)

See all DTYMK antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1E6

Application

IF, WB

Immunogen

Full length recombinant protein of human DTYMK produced in HEK293T cells.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:2,000
IF(ICC)	1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

BSA & Glycerol & PBS

Preservative

Sodium Azide

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

deoxythymidylate kinase (thymidylate kinase)

Entrez Gene ID

1841

UniProt ID

P23919

Research Area

Catalyzes the conversion of dTMP to dTDP.

Biological Process

Cellular response to growth factor stimulus Source: Ensembl
dTDP biosynthetic process Source: GO_Central
dTTP biosynthetic process Source: GO_Central
dUDP biosynthetic process Source: GO_Central
Myoblast differentiation Source: Ensembl
Response to cadmium ion Source: Ensembl
Response to estrogen Source: Ensembl
Thymidine biosynthetic process Source: GO_Central

Cellular Location

Cytosol; Mitochondrial intermembrane space; Mitochondrial matrix; Mitochondrion; Nucleus; Cytoplasm

Vanoevelen, J. M., Bierau, J., Grashorn, J. C., Lambrichs, E., Kamsteeg, E. J., Bok, L. A., ... & Stumpel, C. T. (2022). DTYMK is essential for genome integrity and neuronal survival. Acta neuropathologica, 143(2), 245-262.

Sun, F., Liu, Y., Gong, T., Pan, Q., Xiang, T., Zhao, J., ... & Xia, J. (2021). Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin. Cell death & disease, 12(12), 1-9.

Guo, Y., Luo, W., Huang, S., Zhao, W., Chen, H., Ma, Y., ... & Chen, M. (2021). DTYMK Expression Predicts Prognosis and Chemotherapeutic Response and Correlates with Immune Infiltration in Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma, 8, 871.

He, G., Qiu, J., Liu, C., Tian, B., Cai, D., & Liu, S. (2021). MiR-148b-3p Regulates the Expression of DTYMK to Drive Hepatocellular Carcinoma Cell Proliferation and Metastasis. Frontiers in oncology, 11.

Lam, C. W., Yeung, W. L., Ling, T. K., Wong, K. C., & Law, C. Y. (2019). Deoxythymidylate kinase, DTYMK, is a novel gene for mitochondrial DNA depletion syndrome. Clinica Chimica Acta, 496, 93-99.

Beckley, A. (2019). Investigation of deoxythymidylate kinase (dTYMK) as an imaging and therapeutic target (Doctoral dissertation, Imperial College London).

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-DTYMK Recombinant Antibody (1E6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-DTYMK Recombinant Antibody (1E6) (CAT#: CBMAB-D1859-YC)

Related Products

Mouse Anti-DTYMK Recombinant Antibody (1E6) (CAT#: CBMAB-D1859-YC)

Mouse Anti-DTYMK Recombinant Antibody (1G8) (CAT#: CBMAB-D1860-YC)

Mouse Anti-DTYMK Recombinant Antibody (2G11) (CAT#: V2LY-0425-LY1043)

Mouse Anti-DTYMK Recombinant Antibody (CBYJT-1201) (CAT#: CBMAB-T0215-YJ)

Mouse Anti-DTYMK Recombinant Antibody (CBYJT-1202) (CAT#: CBMAB-T0216-YJ)

Mouse Anti-DTYMK Recombinant Antibody (CBYJT-1201) (CAT#: V2LY-0425-LY1044)

Mouse Anti-DTYMK Recombinant Antibody (CBYJT-1202) (CAT#: V2LY-0425-LY1045)

Mouse Anti-DTYMK Recombinant Antibody (2G11) (CAT#: CBMAB-D1865-YC)

Mouse Anti-DTYMK Recombinant Antibody (1G8) (CAT#: V2LY-0425-LY1042)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry