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Mouse Anti-GPN1 (AA 9-119) Recombinant Antibody (CBFYH-0447) (CBMAB-H1321-FY)

This product is mouse antibody that recognizes GPN1. The antibody CBFYH-0447 can be used for immunoassay techniques such as: ELISA, IF, IHC-P.
See all GPN1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0447
Antibody Isotype
IgG1
Application
ELISA, IF, IHC-P

Basic Information

Immunogen
Recombinant human XAB1.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 9-119

Target

Full Name
GPN-Loop GTPase 1
Introduction
This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described.
Entrez Gene ID
11321
UniProt ID
Q9HCN4
Alternative Names
GPN-Loop GTPase 1; RNA Polymerase II Associated Protein 4; XPA Binding Protein 1, GTPase; RNAPII-Associated Protein 4; MBD2-Interacting Protein; MBDIN; RPAP4; XAB1
Function
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307).

May act at an RNAP assembly step prior to nuclear import (PubMed:21768307).

Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375).

May be involved in nuclear localization of XPA (PubMed:11058119).
Cellular Location
Nucleus; Cytoplasm. Shuttles between the nucleus and the cytoplasm.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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