GPN1

This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described.
Full Name
GPN-Loop GTPase 1
Function
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307).

May act at an RNAP assembly step prior to nuclear import (PubMed:21768307).

Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375).

May be involved in nuclear localization of XPA (PubMed:11058119).
Cellular Location
Nucleus; Cytoplasm. Shuttles between the nucleus and the cytoplasm.
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Anti-GPN1 antibodies

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Mouse Anti-GPN1 Recombinant Antibody (CBYCX-104) (CBMAB-X0041-YC)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCX-104
Application*: WB, P, ICC, IF
Datasheet SDS

Mouse Anti-GPN1 Recombinant Antibody (B-4) (CBMAB-X0042-YC)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: B-4
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-GPN1 Recombinant Antibody (3E1) (CBMAB-A9957-LY)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3E1
Application*: WB, E
Datasheet SDS

Mouse Anti-GPN1 Recombinant Antibody (CBLG1-1625) (CBMAB-G4606-LY)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1625
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-GPN1 Recombinant Antibody (CBLG1-1624) (CBMAB-G4605-LY)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1624
Application*: E, WB
Datasheet SDS

Mouse Anti-GPN1 Recombinant Antibody (CBLG1-1623) (CBMAB-G4604-LY)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1623
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-GPN1 Recombinant Antibody (CBLG1-198) (CBMAB-G0701-LY)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-198
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-GPN1 Recombinant Antibody (CBLG1-197) (CBMAB-G0700-LY)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-197
Application*: E, IC, IH, WB
Datasheet SDS

Mouse Anti-GPN1 (AA 9-119) Recombinant Antibody (CBFYH-0447) (CBMAB-H1321-FY)

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Target: GPN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0447
Application*: E, IF, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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