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Mouse Anti-GPN1 Recombinant Antibody (CBYCX-104) (CBMAB-X0041-YC)

Provided herein is a Mouse monoclonal antibody against Human GPN1. The antibody, clone CBYCX-104, can be used for immunoassay techniques, such as WB, IHC-P, ICC, IF.
See all GPN1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYCX-104
Antibody Isotype
IgG1
Application
WB, IHC-P, ICC, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
GPN-Loop GTPase 1
Introduction
GPN1 is a guanosine triphosphatase enzyme, which is small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). GPN1 acts at an RNAP assembly step prior to nuclear import and forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. GPN1 may be involved in nuclear localization of XPA
Entrez Gene ID
11321
UniProt ID
Q9HCN4
Alternative Names
XAB1; MBDIN; NTPBP; RPAP4; ATPBD1A
Function
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307).

May act at an RNAP assembly step prior to nuclear import (PubMed:21768307).

Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375).

May be involved in nuclear localization of XPA (PubMed:11058119).
Cellular Location
Nucleus; Cytoplasm. Shuttles between the nucleus and the cytoplasm.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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