Sign in or Register   Sign in or Register
  |  

Mouse Anti-TAC3 Recombinant Antibody (1B2) (CBMAB-N4324-WJ)

This product is a Mouse antibody that recognizes TAC3. The antibody 1B2 can be used for immunoassay techniques such as: WB, IP, ELISA.
See all TAC3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B2
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
tachykinin 3
Introduction
TAC3 (Tachykinin 3) is a Protein Coding gene. Diseases associated with TAC3 include Hypogonadotropic Hypogonadism 10 With Or Without Anosmia and Normosmic Congenital Hypogonadotropic Hypogonadism. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include signaling receptor binding.
Entrez Gene ID
6866
UniProt ID
Q9UHF0
Alternative Names
NKB; HH10; NKNB; PRO1155; ZNEUROK1
Function
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles (By similarity).
Is a critical central regulator of gonadal function.
Biological Process
Biological Process female pregnancyTAS:ProtInc1 Publication
Biological Process neuropeptide signaling pathwayIEA:UniProtKB-KW
Biological Process positive regulation of blood pressureIBA:GO_Central1 Publication
Biological Process positive regulation of flagellated sperm motilityIDA:UniProtKB
Biological Process tachykinin receptor signaling pathwayTAS:ProtInc1 Publication
Cellular Location
Secreted
Involvement in disease
Hypogonadotropic hypogonadism 10 with or without anosmia (HH10):
A disorder characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. In some cases, it is associated with non-reproductive phenotypes, such as anosmia, cleft palate, and sensorineural hearing loss. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In the presence of anosmia, idiopathic hypogonadotropic hypogonadism is referred to as Kallmann syndrome, whereas in the presence of a normal sense of smell, it has been termed normosmic idiopathic hypogonadotropic hypogonadism (nIHH).
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TAC3 Recombinant Antibody (1B2)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare