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Mouse Anti-TGIF2 Recombinant Antibody (CBYJT-2846) (CBMAB-T2072-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TGIF2 (TGFB Induced Factor Homeobox 2). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TGIF2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2846
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa131-237 from human TGIF2 (NP_068581) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 131-237

Target

Full Name
TGIF2 Gene(Protein Coding) TGFB Induced Factor Homeobox 2
Introduction
TGIF2 is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. TGIF2 is amplified and over-expressed in some ovarian cancers.
Entrez Gene ID
60436
UniProt ID
Q9GZN2
Alternative Names
TGFB Induced Factor Homeobox 2; TGFB-Induced Factor 2 (TALE Family Homeobox); TGF-Beta-Induced Transcription Factor 2; TGFB-Induced Factor Homeobox 2; 5-TG-3-Interacting Factor 2; TGFB-Induced Factor 2
Function
Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
Biological Process
Biological Process amacrine cell differentiationSource:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IISource:BHF-UCL1 Publication
Biological Process nodal signaling pathwaySource:Ensembl
Biological Process positive regulation of amacrine cell differentiationSource:Ensembl
Biological Process regulation of DNA-templated transcriptionSource:UniProtKB1 Publication
Biological Process regulation of gastrulationSource:Ensembl
Biological Process regulation of transcription by RNA polymerase IISource:GO_Central1 Publication
Cellular Location
Nucleus
Excluded from nucleoli.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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