MKNK1 Matched Antibody Pair (737) (APMAB-737LY)

Name: MKNK1 Matched Antibody Pair (737)
SKU: APMAB-737LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-MKNK1 monoclonal antibody, 100 ug

Detection Antibody

Anti-MKNK1 Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]

Alternative Names

MAP Kinase Interacting Serine/Threonine Kinase 1; MAP Kinase Signal-Integrating Kinase 1; MAPK Signal-Integrating Kinase 1; EC 2.7.11.1; MNK1; MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1; EC 2.7.11;

Entrez Gene ID

8569

UniProt ID

Q9BUB5

More Infomation

References

Huang, T., Chen, C., Du, J., Zheng, Z., Ye, S., Fang, S., & Liu, K. (2023). A tRF‐5a fragment that regulates radiation resistance of colorectal cancer cells by targeting MKNK1. Journal of Cellular and Molecular Medicine, 27(24), 4021-4033.

Huang, Y., Luo, J., Zhang, Y., Zhang, T., Fei, X., Chen, L., ... & Zhou, J. (2023). Identification of MKNK1 and TOP3A as ovarian endometriosis risk-associated genes using integrative genomic analyses and functional experiments. Computational and Structural Biotechnology Journal, 21, 1510-1522.

Zhang, P., Li, X., Zhang, S., Wu, S., Xiao, Q., Gu, Y., ... & Zhu, L. (2021). miR-370-3p regulates adipogenesis through targeting Mknk1. Molecules, 26(22), 6926.

Fu, M., & Zhang, K. (2021). MAPK interacting serine/threonine kinase 1 (MKNK1), one target gene of miR-223-3p, correlates with neutrophils in sepsis based on bioinformatic analysis. Bioengineered, 12(1), 2550-2562.

Wang, C., Song, J., Liu, W., Yao, Y., Kapranov, P., Sample, K. M., ... & Ben‑David, Y. (2020). FLI1 promotes protein translation via the transcriptional regulation of MKNK1 expression. International Journal of Oncology, 56(2), 430-438.

Liu, K., He, B., Xu, J., Li, Y., Guo, C., Cai, Q., & Wang, S. (2019). miR-483-5p targets MKNK1 to suppress Wilms’ tumor cell proliferation and apoptosis in vitro and in vivo. Medical science monitor: international medical journal of experimental and clinical research, 25, 1459.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

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Rabbit Anti-MKNK1 Recombinant Antibody (CBFYM-2262)

Mouse Anti-MKNK1 (AA 1-362) Recombinant Antibody (CBFYM-2263)

Mouse Anti-MKNK1 Recombinant Antibody (3C9)

Mouse Anti-MKNK1 Recombinant Antibody (3G6)

Mouse Anti-MKNK1 Recombinant Antibody (5E2)

Rabbit Anti-MKNK1 Recombinant Antibody (C4C1)

Mouse Anti-MKNK1 (AA 1-466) Recombinant Antibody (CBFYM-2261)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
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Second antibody and isotype control

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