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AFAP1

AFAP1 is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments.
Full Name
Actin Filament Associated Protein 1
Function
Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Biological Process
Regulation of cytoskeleton organization
Regulation of signal transduction
Cellular Location
Stress fiber
PTM
Phosphorylated on tyrosine residues by SRC.
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Anti-AFAP1 antibodies

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Mouse Anti-AFAP1 Recombinant Antibody (V2-611022) (CBMAB-A0175-LY)

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Target: AFAP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-611022
Application*: E
Datasheet SDS

Mouse Anti-AFAP1 Recombinant Antibody (V2-180043) (CBMAB-A1450-YC)

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Target: AFAP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-180043
Application*: P, WB
Datasheet SDS

Mouse Anti-AFAP1 Recombinant Antibody (V2-180041) (CBMAB-A1448-YC)

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Target: AFAP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-180041
Application*: WB
Datasheet SDS

Mouse Anti-AFAP1 Recombinant Antibody (V2-180040) (CBMAB-A1447-YC)

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Target: AFAP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-180040
Application*: F, E
Datasheet SDS

Mouse Anti-AFAP1 Recombinant Antibody (V2-12536) (CBMAB-1026-CN)

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Target: AFAP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-12536
Application*: E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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