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CD1a

CD1A (CD1a Molecule) is a Protein Coding gene. Diseases associated with CD1A include Langerhans Cell Histiocytosis and Histiocytosis. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1B.
Full Name
CD1a Molecule
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Antigen processing and presentation, endogenous lipid antigen via MHC class Ib Source: GO_Central
Antigen processing and presentation, exogenous lipid antigen via MHC class Ib Source: GO_Central
Immune response Source: UniProtKB
Positive regulation of T cell mediated cytotoxicity Source: GO_Central
Regulation of immune response Source: Reactome
Cellular Location
Endosome membrane; Cell membrane; Membrane raft. Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838).
Topology
Extracellular: 17-300
Helical: 301-321
Cytoplasmic: 322-327

Anti-CD1a antibodies

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Mouse Anti-CD1A Recombinant Antibody (CBXC-3023) (CBMAB-C4031-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-3023
Application*: WB, F, E

Mouse Anti-CD1A Recombinant Antibody (CBXC-2287) (CBMAB-C4030-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-2287
Application*: F

Mouse Anti-CD1A Recombinant Antibody (SK9) (CBMAB-C2233-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: SK9
Application*: F, IP

Mouse Anti-CD1A Recombinant Antibody (HI149) (CBMAB-C1771-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HI149
Application*: F

Mouse Anti-CD1A Recombinant Antibody (O10) (CBMAB-C0962-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: O10
Application*: WB, F, E, IF, IP, P, C, MC

Mouse Anti-CD1A Recombinant Antibody (NA1/34-HLK) (CBMAB-C0955-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog
Clone: NA1/34-HLK
Application*: F

Mouse Anti-CD1A Recombinant Antibody (CBT6) (CBMAB-C0527-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBT6
Application*: F, IF

Rabbit Anti-CD1A Recombinant Antibody (C1A/1506R) (CBMAB-C0463-CQ)

Datasheet SDS
Target: CD1A
Host: Rabbit
Antibody Isotype: IgG, κ
Specificity: Human
Clone: C1A/1506R
Application*: F, IF, P

Mouse Anti-CD1A Recombinant Antibody (CBXC-2513) (CBMAB-C0091-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBXC-2513
Application*: F, IH, IF

Mouse Anti-CD1A Recombinant Antibody (CBXC-2712) (CBMAB-C0084-CQ)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2712
Application*: F, IH, IF, IC

Mouse Anti-CD1A Recombinant Antibody (CBFYC-1135) (CBMAB-C1193-FY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1135
Application*: F, IH, IF, IC

Mouse Anti-CD1A Recombinant Antibody (CBFYC-1134) (CBMAB-C1192-FY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1134
Application*: E, F, WB

Mouse Anti-CD1A Recombinant Antibody (CBFYC-0443) (CBMAB-C0489-FY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBFYC-0443
Application*: F, IH, IF

Mouse Anti-CD1A (AA 1-300) Recombinant Antibody (CBFYC-0387) (CBMAB-C0428-FY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0387
Application*: F

Mouse Anti-CD1A Recombinant Antibody (7A7) (CBMAB-C8565-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7A7
Application*: E, IC/IF, WB

Mouse Anti-CD1A Recombinant Antibody (703217) (CBMAB-C8405-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 703217
Application*: F, IC, MC

Mouse Anti-CD1A Recombinant Antibody (6H3) (CBMAB-C8350-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6H3
Application*: C, WB

Mouse Anti-CD1A Recombinant Antibody (66IIC7) (CBMAB-C7932-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 66IIC7
Application*: F, IF, P

Mouse Anti- CD1a Recombinant Antibody (OKT-6) (CBMAB-0918-LY)

Datasheet SDS
Target: CD1a
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: OKT-6
Application*: B, F

Mouse Anti-CD1A Recombinant Antibody (C1A/711) (CBMAB-AP975LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: C1A/711
Application*: FC, IF, IHC

Mouse Anti-CD1A Recombinant Antibody (SPM120) (CBMAB-AP972LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM120
Application*: FC, IF, IHC

Mouse Anti-CD1A Recombinant Antibody (479) (CBMAB-AP970LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 479
Application*: ELISA, WB

Mouse Anti-CD1A Recombinant Antibody (CAP384) (CBMAB-AP968LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP384
Application*: ELISA, IHC

Mouse Anti-CD1A Recombinant Antibody (CF068) (CBMAB-FT394LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF068
Application*: ELISA, WB

Mouse Anti-CD1A Recombinant Antibody (CB210A) (CBMAB-CA210LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB210A
Application*: ELISA, IHC

Mouse Anti-CD1A Recombinant Antibody (IHC530) (CBMAB-MA035-YC)

Datasheet SDS
Target: CD1A
Host: Mouse
Specificity: Human
Clone: IHC530
Application*: IH

Mouse Anti-CD1A Recombinant Antibody (5G34) (CBMAB-C7674-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5G34
Application*: E, IH

Mouse Anti-CD1A Recombinant Antibody (5F1) (CBMAB-C7530-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5F1
Application*: F, IF, IH

Mouse Anti-CD1A Recombinant Antibody (437CT28.2.1) (CBMAB-C6486-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 437CT28.2.1
Application*: WB, E

Mouse Anti-CD1A Recombinant Antibody (3F64) (CBMAB-C6060-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3F64
Application*: IH

Mouse Anti-CD1A Recombinant Antibody (2C2B4) (CBMAB-C4772-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2C2B4
Application*: E, WB

Mouse Anti-CD1A Recombinant Antibody (13B118) (CBMAB-C2775-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B118
Application*: E, C, WB

Mouse Anti-CD1A Recombinant Antibody (3H639) (CBMAB-C1230-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Monkey
Clone: 3H639
Application*: F, IH

Mouse Anti-CD1A Recombinant Antibody (214A9.01) (CBMAB-C0628-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 214A9.01
Application*: F, IH, P, C

Mouse Anti-CD1A Recombinant Antibody (04-07-76) (CBMAB-C0075-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Pig
Clone: 04-07-76
Application*: C, F, IP

Mouse Anti-CD1A Recombinant Antibody (MTB1) (CBMAB-C10036-LY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MTB1
Application*: C, P

Mouse Anti-CD1A Recombinant Antibody (CBCNC-160) (CBMAB-C1584-CN)

Datasheet SDS
Target: CD1A
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBCNC-160
Application*: IH

Rabbit Anti-CD1A Recombinant Antibody (SP157) (CBMAB-C1583-CN)

Datasheet SDS
Target: CD1A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP157
Application*: P

Mouse Anti-CD1A Recombinant Antibody (O10+C1A/711) (CBMAB-C1582-CN)

Datasheet SDS
Target: CD1A
Host: Mouse
Specificity: Human
Clone: O10+C1A/711
Application*: FC, IF, IH, IP, WB

Mouse Anti-CD1A Recombinant Antibody (MT1B) (CBMAB-C1581-CN)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: MT1B
Application*: IH

Mouse Anti-CD1A Recombinant Antibody (MCD1a) (CBMAB-C1580-CN)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MCD1a
Application*: IF, FC

Mouse Anti-CD1A Recombinant Antibody (CB-T6) (CBMAB-C1578-CN)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB-T6
Application*: FC

Mouse Anti-CD1A Recombinant Antibody (BL-THY 1) (CBMAB-C1576-CN)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BL-THY 1
Application*: E, FC, IH

Mouse Anti-CD1A Recombinant Antibody (CBYY-C1212) (CBMAB-C2649-YY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1212
Application*: E, IH

Mouse Anti-CD1A Recombinant Antibody (CBYY-C1210) (CBMAB-C2647-YY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1210
Application*: IH

Mouse Anti-CD1A Recombinant Antibody (CBYY-C0570) (CBMAB-C1766-YY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Pig
Clone: CBYY-C0570
Application*: C, IP, F

Mouse Anti-CD1A Recombinant Antibody (CBYY-C0173) (CBMAB-C0535-YY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Dog, Human, Monkey
Clone: CBYY-C0173
Application*: F

Mouse Anti-CD1A Recombinant Antibody (CBYY-C0172) (CBMAB-C0534-YY)

Datasheet SDS
Target: CD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Dog, Human, Monkey
Clone: CBYY-C0172
Application*: F, IH

Rabbit Anti-CD1A Monoclonal Antibody (EP3622) (CBMAB-R0020-FY)

Datasheet SDS
Target: CD1A
Host: Rabbit
Antibody Isotype: IgG1
Specificity: Human
Clone: EP3622
Application*: ELISA
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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