CD38
CD38 (CD38 Molecule) is a Protein Coding gene. Diseases associated with CD38 include Richter's Syndrome and Leukemia, Chronic Lymphocytic. Among its related pathways are Cell-type Dependent Selectivity of CCK2R Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.
Full Name
CD38 Molecule
Alternative Names
CD38 Molecule; ADP-Ribosyl Cyclase 1; 2-Phospho-Cyclic-ADP-Ribose Transferase; Cyclic ADP-Ribose Hydrolase 1; 2-Phospho-ADP-Ribosyl Cyclase; NAD(+) Nucleosidase; CD38 Antigen (P45); ADPRC 1; 2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase;
Function
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Biological Process
Apoptotic signaling pathway Source: ProtInc
Artery smooth muscle contraction Source: Ensembl
B cell receptor signaling pathway Source: UniProtKB
Female pregnancy Source: Ensembl
Long-term synaptic depression Source: Ensembl
NAD metabolic process Source: Reactome
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of bone resorption Source: Ensembl
Negative regulation of neuron projection development Source: Ensembl
Negative regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of B cell proliferation Source: UniProtKB
Positive regulation of cell growth Source: Ensembl
Positive regulation of cytosolic calcium ion concentration Source: Ensembl
Positive regulation of insulin secretion Source: Ensembl
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of vasoconstriction Source: Ensembl
Response to drug Source: UniProtKB
Response to estradiol Source: Ensembl
Response to hydroperoxide Source: Ensembl
Response to hypoxia Source: Ensembl
Response to interleukin-1 Source: Ensembl
Response to progesterone Source: Ensembl
Response to retinoic acid Source: Ensembl
Signal transduction Source: ProtInc
Artery smooth muscle contraction Source: Ensembl
B cell receptor signaling pathway Source: UniProtKB
Female pregnancy Source: Ensembl
Long-term synaptic depression Source: Ensembl
NAD metabolic process Source: Reactome
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of bone resorption Source: Ensembl
Negative regulation of neuron projection development Source: Ensembl
Negative regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of B cell proliferation Source: UniProtKB
Positive regulation of cell growth Source: Ensembl
Positive regulation of cytosolic calcium ion concentration Source: Ensembl
Positive regulation of insulin secretion Source: Ensembl
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of vasoconstriction Source: Ensembl
Response to drug Source: UniProtKB
Response to estradiol Source: Ensembl
Response to hydroperoxide Source: Ensembl
Response to hypoxia Source: Ensembl
Response to interleukin-1 Source: Ensembl
Response to progesterone Source: Ensembl
Response to retinoic acid Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Membrane
Topology
Cytoplasmic: 1-21
Helical: 22-42
Extracellular: 43-300
Helical: 22-42
Extracellular: 43-300
View more
Anti-CD38 antibodies
+ Filters
Loading...
CompareTarget: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Monkey
Clone: AG25
Application*: F
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AT13/5
Application*: WB, IP, IF, F
Target: CD38
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT300
Application*: WB, P, IF, E
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3107
Application*: IH
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3735
Application*: WB, IH
Target: CD38
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0882
Application*: F, E
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AT1
Application*: WB, IP, IF, F, P
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1252
Application*: P
Target: CD38
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1250
Application*: E, F
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1248
Application*: WB, IP, IF, E, P
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-1247
Application*: WB, IP, IF, F
Target: CD38
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBFYC-1246
Application*: F, IF, E, in vivo
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 017
Application*: P
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 003
Application*: WB, E, IP
More Infomation
Hot products 
-
Mouse Anti-COL12A1 Recombinant Antibody (CBYY-C3117) (CBMAB-C4560-YY)
-
Mouse Anti-AMH Recombinant Antibody (5/6) (CBMAB-A2527-YC)
-
Mouse Anti-AP4E1 Recombinant Antibody (32) (CBMAB-A2996-YC)
-
Mouse Anti-DLL4 Recombinant Antibody (D1090) (CBMAB-D1090-YC)
-
Mouse Anti-APC Recombinant Antibody (CBYC-A661) (CBMAB-A3036-YC)
-
Mouse Anti-COL1A2 Recombinant Antibody (CF108) (V2LY-1206-LY626)
-
Mouse Anti-ATP1B1 Recombinant Antibody (E4) (CBMAB-0463-LY)
-
Mouse Anti-AOC3 Recombinant Antibody (CBYY-0014) (CBMAB-0014-YY)
-
Mouse Anti-AKR1C3 Recombinant Antibody (V2-12560) (CBMAB-1050-CN)
-
Mouse Anti-CCDC6 Recombinant Antibody (CBXC-0106) (CBMAB-C5397-CQ)
-
Mouse Anti-CARTPT Recombinant Antibody (113612) (CBMAB-C2450-LY)
-
Rabbit Anti-B2M Recombinant Antibody (CBYY-0059) (CBMAB-0059-YY)
-
Mouse Anti-CD19 Recombinant Antibody (CBXC-1224) (CBMAB-C1491-CQ)
-
Mouse Anti-ADV Recombinant Antibody (V2-503423) (CBMAB-V208-1364-FY)
-
Mouse Anti-AQP2 Recombinant Antibody (E-2) (CBMAB-A3358-YC)
-
Mouse Anti-AQP2 Recombinant Antibody (G-3) (CBMAB-A3359-YC)
-
Mouse Anti-APOH Recombinant Antibody (4D9A4) (CBMAB-A3249-YC)
-
Mouse Anti-BIRC3 Recombinant Antibody (315304) (CBMAB-1214-CN)
-
Mouse Anti-8-oxoguanine Recombinant Antibody (V2-7719) (CBMAB-1898CQ)
-
Mouse Anti-CD164 Recombinant Antibody (CBFYC-0077) (CBMAB-C0086-FY)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry