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CD38

CD38 (CD38 Molecule) is a Protein Coding gene. Diseases associated with CD38 include Richter's Syndrome and Leukemia, Chronic Lymphocytic. Among its related pathways are Cell-type Dependent Selectivity of CCK2R Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.
Full Name
CD38 Molecule
Function
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Biological Process
Apoptotic signaling pathway Source: ProtInc
Artery smooth muscle contraction Source: Ensembl
B cell receptor signaling pathway Source: UniProtKB
Female pregnancy Source: Ensembl
Long-term synaptic depression Source: Ensembl
NAD metabolic process Source: Reactome
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of bone resorption Source: Ensembl
Negative regulation of neuron projection development Source: Ensembl
Negative regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of B cell proliferation Source: UniProtKB
Positive regulation of cell growth Source: Ensembl
Positive regulation of cytosolic calcium ion concentration Source: Ensembl
Positive regulation of insulin secretion Source: Ensembl
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of vasoconstriction Source: Ensembl
Response to drug Source: UniProtKB
Response to estradiol Source: Ensembl
Response to hydroperoxide Source: Ensembl
Response to hypoxia Source: Ensembl
Response to interleukin-1 Source: Ensembl
Response to progesterone Source: Ensembl
Response to retinoic acid Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Membrane
Topology
Cytoplasmic: 1-21
Helical: 22-42
Extracellular: 43-300

Anti-CD38 antibodies

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Mouse Anti-CD38 Recombinant Antibody (CBXC-0215) (CBMAB-C4781-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0215
Application*: F, IH, IP

Mouse Anti-CD38 Recombinant Antibody (CBXC-1945) (CBMAB-C4780-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1945
Application*: WB, IH

Mouse Anti-CD38 Recombinant Antibody (CBXC-0214) (CBMAB-C4779-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0214
Application*: E, P, WB

Rat Anti-CD38 Recombinant Antibody (CBXC-1710) (CBMAB-C3576-CQ)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXC-1710
Application*: F

Rat Anti-CD38 Recombinant Antibody (CBXC-1619) (CBMAB-C2901-CQ)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBXC-1619
Application*: F, IH, IP

Mouse Anti-CD38 Recombinant Antibody (CBXC-1034) (CBMAB-C1297-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-1034
Application*: F

Mouse Anti-CD38 Recombinant Antibody (CBXC-3092) (CBMAB-C0913-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-3092
Application*: F, IH, P

Mouse Anti-CD38 Recombinant Antibody (HIT2) (CBMAB-C0708-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HIT2
Application*: WB, F, IH, P, C, MC

Mouse Anti-CD38 Recombinant Antibody (HB7) (CBMAB-C0684-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HB7
Application*: F

Mouse Anti-CD38 Recombinant Antibody (FS02) (CBMAB-C4785-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: FS02
Application*: F, IF

Mouse Anti-CD38 Recombinant Antibody (AT2) (CBMAB-C4784-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: AT2
Application*: F, IF

Mouse Anti-CD38 Recombinant Antibody (CBXC-0217) (CBMAB-C4783-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0217
Application*: F, C, P, IP

Human Anti-CD38 Recombinant Antibody (CBXC-0882) (CBMAB-C1997-CQ)

Datasheet SDS
Target: CD38
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0882
Application*: F

Mouse Anti-CD38 Recombinant Antibody (CBFYC-0465) (CBMAB-C0511-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0465
Application*: WB, IP

Mouse Anti-CD38 (AA 71-197) Recombinant Antibody (CBFYC-0407) (CBMAB-C0449-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Mouse
Clone: CBFYC-0407
Application*: P, WB

Rat Anti-CD38 Recombinant Antibody (3H1268) (CBMAB-C1160-LY)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 3H1268
Application*: F, IH, IP

Mouse Anti-CD38 Recombinant Antibody (1G7F4) (CBMAB-C0540-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Mouse, Human
Clone: 1G7F4
Application*: WB, IH, IC/IF, P, C

Mouse Anti-CD38 Recombinant Antibody (AT1) (CBMAB-C0405-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AT1
Application*: F, IF, MC

Mouse Anti-CD38 Recombinant Antibody (CBXC-2696) (CBMAB-C0075-CQ)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Human, Mouse
Clone: CBXC-2696
Application*: WB, IH, P

Mouse Anti-CD38 Recombinant Antibody (CBYY-C1347) (CBMAB-C2785-YY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-C1347
Application*: F, IH

Rat Anti-CD38 Recombinant Antibody (CBYY-C0722) (CBMAB-C2133-YY)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-C0722
Application*: F

Mouse Anti-CD38 Recombinant Antibody (CBYY-C0615) (CBMAB-C1903-YY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0615
Application*: E, F, WB

Rat Anti-CD38 Recombinant Antibody (CBYY-C0425) (CBMAB-C1381-YY)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-C0425
Application*: F, IH, IP

Mouse Anti-CD38 Recombinant Antibody (CBFYC-1256) (CBMAB-C1314-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-1256
Application*: F, IF, IH

Mouse Anti-CD38 Recombinant Antibody (CBFYC-1255) (CBMAB-C1313-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1255
Application*: E

Rabbit Anti-CD38 Recombinant Antibody (CBFYC-1253) (CBMAB-C1311-FY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1253
Application*: WB, E

Rabbit Anti-CD38 Recombinant Antibody (CBFYC-1252) (CBMAB-C1310-FY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1252
Application*: P

Mouse Anti-CD38 Recombinant Antibody (AT13/5) (CBMAB-C0449-CN)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT13/5
Application*: IH, IP, FC, P

Mouse Anti-CD38 (AA 171-292) Recombinant Antibody (CBFYC-1251) (CBMAB-C1309-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1251
Application*: WB, IF

Rabbit Anti-CD38 (AA 43-300) Recombinant Antibody (CBFYC-1250) (CBMAB-C1308-FY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1250
Application*: E

Mouse Anti-CD38 Recombinant Antibody (CBFYC-1248) (CBMAB-C1306-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1248
Application*: IH

Mouse Anti-CD38 Recombinant Antibody (CBFYC-1247) (CBMAB-C1305-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBFYC-1247
Application*: F, IH

Rat Anti-CD38 Recombinant Antibody (CBFYC-1246) (CBMAB-C1304-FY)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-1246
Application*: F, IH

Mouse Anti-CD38 Recombinant Antibody (CBFYC-1245) (CBMAB-C1303-FY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Rat
Clone: CBFYC-1245
Application*: F

Rat Anti-CD38 Recombinant Antibody (90) (CBMAB-C9305-LY)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 90
Application*: C, FN, IH

Rat Anti-CD38 Recombinant Antibody (5K14) (CBMAB-C7771-LY)

Datasheet SDS
Target: CD38
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 5K14
Application*: F, IH, IP

Rabbit Anti-CD38 Recombinant Antibody (32) (CBMAB-C5490-LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 32
Application*: E, WB, P

Mouse Anti-CD38 Recombinant Antibody (4AHIT2) (CBMAB-EN638-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4AHIT2
Application*: FC, IF, IHC, WB

Mouse Anti-CD38 Recombinant Antibody (A049) (CBMAB-AP10657LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A049
Application*: FC, IHC

Rabbit Anti-CD38 Recombinant Antibody (HB7) (CBMAB-AP1064LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: HB7
Application*: FC, WB

Mouse Anti-CD38 Recombinant Antibody (2A1) (CBMAB-AP1059LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2A1
Application*: IHC

Mouse Anti-CD38 Recombinant Antibody (33) (CBMAB-AP1058LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 33
Application*: ELISA, IF, WB

Mouse Anti-CD38 Recombinant Antibody (TME-2) (CBMAB-AP1057LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TME-2
Application*: FC

Mouse Anti-CD38 Recombinant Antibody (CF075) (CBMAB-FT401LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF075
Application*: ELISA, IF, WB

Mouse Anti-CD38 Recombinant Antibody (CB107A) (CBMAB-CA107LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CB107A
Application*: ELISA, IHC

Mouse Anti-CD38 Recombinant Antibody (CB073) (CBMAB-CS073LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB073
Application*: IF, FC

Mouse Anti-CD38 Recombinant Antibody (CB072) (CBMAB-CS072LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB072
Application*: IF, FC

Mouse Anti-CD38 Recombinant Antibody (CB071) (CBMAB-CS071LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB071
Application*: IF, FC

Mouse Anti-CD38 Recombinant Antibody (TB2) (CBMAB-C10238-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TB2
Application*: IF/IC, C

Mouse Anti-CD38 Recombinant Antibody (SPC32) (CBMAB-C10236-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: SPC32
Application*: C, P

Rabbit Anti-CD38 Recombinant Antibody (SP149) (CBMAB-C10235-LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: SP149
Application*: F

Mouse Anti-CD38 Recombinant Antibody (T16) (CBMAB-C10237-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: T16
Application*: IC/IF, F

Mouse Anti-CD38 Recombinant Antibody (IHC038) (CBMAB-MA044-YC)

Datasheet SDS
Target: CD38
Host: Mouse
Specificity: Human
Clone: IHC038
Application*: IH

Mouse Anti-CD38 Recombinant Antibody (CB070) (CBMAB-CS070LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB070
Application*: IF, FC

Mouse Anti-CD38 Recombinant Antibody (OKT10) (CBMAB-A4284-YC)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: OKT10
Application*: F

Mouse Anti-CD38 Recombinant Antibody (CBYC-A931) (CBMAB-A4285-YC)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A931
Application*: WB

Mouse Anti-CD38 Recombinant Antibody (240726) (CBMAB-C0710-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 240726
Application*: WB, IP

Mouse Anti-CD38 Recombinant Antibody (240742) (CBMAB-C0711-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 240742
Application*: F, IP, IC, MC

Mouse Anti-CD38 Recombinant Antibody (38C03) (CBMAB-C1057-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 38C03
Application*: P

Mouse Anti-CD38 Recombinant Antibody (0.N.109) (CBMAB-C1384-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 0.N.109
Application*: F, IF, IH

Mouse Anti-CD38 Recombinant Antibody (0.N.110) (CBMAB-C1385-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 0.N.110
Application*: IH

Rabbit Anti-CD38 Recombinant Antibody (003) (CBMAB-C1490-LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 003
Application*: WB, E

Rabbit Anti-CD38 Recombinant Antibody (017) (CBMAB-C1636-LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 017
Application*: P

Rabbit Anti-CD38 Recombinant Antibody (067) (CBMAB-C1831-LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 067
Application*: EC

Mouse Anti-CD38 Recombinant Antibody (0-N-110) (CBMAB-C1886-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 0-N-110
Application*: IH

Rabbit Anti-CD38 Recombinant Antibody (11) (CBMAB-C2412-LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 11
Application*: E

Mouse Anti-CD38 Recombinant Antibody (14L202) (CBMAB-C3119-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L202
Application*: F, IH

Rabbit Anti-CD38 Recombinant Antibody (3) (CBMAB-C5427-LY)

Datasheet SDS
Target: CD38
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 3
Application*: E, WB

Mouse Anti-CD38 Recombinant Antibody (4G3) (CBMAB-C6986-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4G3
Application*: E, IF, WB

Mouse Anti-CD38 Recombinant Antibody (5C5C3) (CBMAB-C7398-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C5C3
Application*: WB, P

Mouse Anti-CD38 Recombinant Antibody (5F33) (CBMAB-C7609-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5F33
Application*: F, IF, IH

Mouse Anti-CD38 Recombinant Antibody (6E12D) (CBMAB-C8239-LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6E12D
Application*: E, P, WB

Mouse Anti-CD38 Recombinant Antibody (CB069) (CBMAB-CS069LY)

Datasheet SDS
Target: CD38
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB069
Application*: IF, FC
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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