DNER

DNER (Delta/Notch Like EGF Repeat Containing) is a Protein Coding gene. Among its related pathways are Signaling by NOTCH1 and NOTCH2 Activation and Transmission of Signal to the Nucleus. Gene Ontology (GO) annotations related to this gene include calcium ion binding and clathrin binding. An important paralog of this gene is CRB1.
Full Name
delta/notch-like EGF repeat containing
Function
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Biological Process
Central nervous system development Source: UniProtKB
Endocytosis Source: UniProtKB
Glial cell differentiation Source: Ensembl
Neuron migration Source: UniProtKB
Notch receptor processing Source: Ensembl
Notch signaling pathway Source: UniProtKB-KW
Skeletal muscle fiber development Source: Ensembl
Synapse assembly Source: UniProtKB
Cellular Location
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
Topology
Extracellular: 35-640
Helical: 641-661
Cytoplasmic: 662-737
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Anti-DNER antibodies

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Mouse Anti-DNER Recombinant Antibody (4E8) (CBMAB-1037-YC)

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Target: DNER
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 4E8
Application*: E, WB
Datasheet SDS

Rat Anti-DNER Recombinant Antibody (D1355) (V2LY-0425-LY681)

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Target: DNER
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: D1355
Application*: IH, WB
Datasheet SDS

Mouse Anti-DNER Recombinant Antibody (1036) (V2LY-0425-LY678)

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Target: DNER
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse, Rat
Clone: 1036
Application*: E, IP, WB
Datasheet SDS

Mouse Anti-DNER Recombinant Antibody (2F3) (CBMAB-D1354-YC)

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Target: DNER
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 2F3
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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