DSTN

The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
Full Name
Destrin, Actin Depolymerizing Factor
Research Area
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
Biological Process
Actin filament depolymerization Source: UniProtKB
Actin filament fragmentation Source: GO_Central
Actin filament severing Source: GO_Central
Actin polymerization or depolymerization Source: ProtInc
Cell motility Source: GO_Central
Positive regulation of actin filament depolymerization Source: Ensembl
Cellular Location
Actin cytoskeleton; Cortical actin cytoskeleton; Extracellular exosome; Cytoplasm
PTM
ISGylated.
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Anti-DSTN antibodies

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Mouse Anti-DSTN Recombinant Antibody (2F7) (CBMAB-D1825-YC)

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Target: DSTN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 2F7
Application*: F, IF, IH, WB
Datasheet SDS

Mouse Anti-DSTN Recombinant Antibody (2E10) (CBMAB-D1823-YC)

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Target: DSTN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Mouse
Clone: 2E10
Application*: F, IH, WB
Datasheet SDS

Mouse Anti-DSTN Recombinant Antibody (1D8) (CBMAB-D1820-YC)

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Target: DSTN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Monkey, Mouse
Clone: 1D8
Application*: F, IF, IH, WB
Datasheet SDS

Mouse Anti-DSTN Recombinant Antibody (1B8) (CBMAB-D1816-YC)

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Target: DSTN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Pig
Clone: 1B8
Application*: WB
Datasheet SDS

Mouse Anti-DSTN Recombinant Antibody (1G8) (V2LY-0425-LY1017)

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Target: DSTN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 1G8
Application*: F, IH, WB
Datasheet SDS

Rabbit Anti-DSTN Recombinant Antibody (D1817) (V2LY-0425-LY1015)

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Target: DSTN
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D1817
Application*: F, WB, IP, IH, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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