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DSTN

The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
Full Name
Destrin, Actin Depolymerizing Factor
Research Area
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
Biological Process
Actin filament depolymerization Source: UniProtKB
Actin filament fragmentation Source: GO_Central
Actin filament severing Source: GO_Central
Actin polymerization or depolymerization Source: ProtInc
Cell motility Source: GO_Central
Positive regulation of actin filament depolymerization Source: Ensembl
Cellular Location
Actin cytoskeleton; Cortical actin cytoskeleton; Extracellular exosome; Cytoplasm
PTM
ISGylated.

Anti-DSTN antibodies

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Mouse Anti-DSTN Recombinant Antibody (2F7) (CBMAB-D1825-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: 2F7
Application*: F, IF, IH, WB

Mouse Anti-DSTN Recombinant Antibody (2E8) (CBMAB-D1824-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 2E8
Application*: WB, F

Mouse Anti-DSTN Recombinant Antibody (2E10) (CBMAB-D1823-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: 2E10
Application*: IF, WB

Mouse Anti-DSTN Recombinant Antibody (2C10) (CBMAB-D1822-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C10
Application*: F, IH, WB

Mouse Anti-DSTN Recombinant Antibody (1G8) (CBMAB-D1821-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1G8
Application*: P, WB

Mouse Anti-DSTN Recombinant Antibody (1D8) (CBMAB-D1820-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Monkey
Clone: 1D8
Application*: F, IF, IH, WB

Mouse Anti-DSTN Recombinant Antibody (1C5) (CBMAB-D1817-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C5
Application*: F

Mouse Anti-DSTN Recombinant Antibody (1B8) (CBMAB-D1816-YC)

Datasheet SDS
Target: DSTN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1B8
Application*: WB, IH, F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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