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Mouse Anti-DSTN Recombinant Antibody (1G8) (V2LY-0425-LY1017)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
1G8
Antibody Isotype
IgG2a
Application
FC, IHC, WB

Basic Information

Immunogen
Full length recombinant protein of human DSTN produced in HEK293T cells.
Host Species
Mouse
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:2,000
IHC1:150
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
BSA & Glycerol & PBS
Preservative
Sodium Azide
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Destrin, Actin Depolymerizing Factor
Entrez Gene ID
11034
UniProt ID
P60981
Research Area
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
Biological Process
Actin filament depolymerization Source: UniProtKB
Actin filament fragmentation Source: GO_Central
Actin filament severing Source: GO_Central
Actin polymerization or depolymerization Source: ProtInc
Cell motility Source: GO_Central
Positive regulation of actin filament depolymerization Source: Ensembl
Cellular Location
Actin cytoskeleton; Cortical actin cytoskeleton; Extracellular exosome; Cytoplasm
PTM
ISGylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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