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Mouse Anti-DSTN Recombinant Antibody (1D8) (CBMAB-D1820-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Dog, Monkey, Mouse
Clone
1D8
Antibody Isotype
IgG2a
Application
FC, IF, IHC, WB

Basic Information

Immunogen
Full length recombinant protein of human DSTN produced in HEK293T cells.
Host Species
Mouse
Specificity
Human, Dog, Monkey, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500-1:2,000
IF(ICC)1:100
IHC1:150
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
BSA & Glycerol & PBS
Preservative
Sodium Azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Destrin, Actin Depolymerizing Factor
Introduction
DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).
Entrez Gene ID
Human11034
Dog477147
Monkey695969
UniProt ID
HumanP60981
DogJ9P1J5
MonkeyH9EM17
Alternative Names
Destrin, Actin Depolymerizing Factor; Actin-Depolymerizing Factor; ACTDP; ADF; BA462D18.2 (Destrin (Actin Depolymerizing Factor ADF) (ACTDP)); Destrin (Actin Depolymerizing Factor);
Research Area
Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
Biological Process
Actin filament depolymerization Source: UniProtKB
Actin filament fragmentation Source: GO_Central
Actin filament severing Source: GO_Central
Actin polymerization or depolymerization Source: ProtInc
Cell motility Source: GO_Central
Positive regulation of actin filament depolymerization Source: Ensembl
Cellular Location
Actin cytoskeleton; Cortical actin cytoskeleton; Extracellular exosome; Cytoplasm
PTM
ISGylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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