LMNB2

LMNB2 is a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.
Full Name
LMNB2
Function
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Cellular Location
Nucleus lamina
Involvement in disease
Partial acquired lipodystrophy (APLD):
A rare childhood disease characterized by loss of subcutaneous fat from the face and trunk. Fat deposition on the pelvic girdle and lower limbs is normal or excessive. Most frequently, onset between 5 and 15 years of age. Most affected subjects are females and some show no other abnormality, but many develop glomerulonephritis, diabetes mellitus, hyperlipidemia, and complement deficiency. Mental retardation in some cases. APLD is a sporadic disorder of unknown etiology.
Epilepsy, progressive myoclonic 9 (EPM9):
A form of progressive myoclonic epilepsy, a clinically and genetically heterogeneous group of disorders defined by the combination of action and reflex myoclonus, other types of epileptic seizures, and progressive neurodegeneration and neurocognitive impairment. EPM9 is an autosomal recessive form characterized by myoclonus, tonic-clonic seizures, ataxia, and delayed psychomotor development.
Microcephaly 27, primary, autosomal dominant (MCPH27):
A form of microcephaly, a disease defined as a head circumference more than 3 standard deviations below the age, sex and ethnically matched mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. MCPH27 is an autosomal dominant form apparent in early childhood and associated with global developmental delay, delayed walking, inability to walk, impaired intellectual development, and poor or absent speech. Brain imaging may show enlarged ventricles or gyral abnormalities in some patients.
PTM
B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
View more

Anti-LMNB2 antibodies

+ Filters
Loading...

Rabbit Anti-LMNB2 Recombinant Antibody (E1S1Q) (CBMAB-CP1341-LY)

Go to compareCompare
Target: LMNB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: E1S1Q
Application*: WB
Datasheet SDS

Rabbit Anti-LMNB2 Recombinant Antibody (D8P3U) (CBMAB-CP1340-LY)

Go to compareCompare
Target: LMNB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: D8P3U
Application*: WB, IP, IF (IC)
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (X67) (CBMAB-P0471-YC)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Cattle, Frog
Clone: X67
Application*: WB, IC, IF
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBYCL-389) (CBMAB-L0290-YC)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-389
Application*: F, C, WB
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBYCL-387) (CBMAB-L0288-YC)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-387
Application*: F, IC, WB
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBYCL-386) (CBMAB-L0287-YC)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYCL-386
Application*: WB, IH
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBYCL-385) (CBMAB-L0286-YC)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Chicken
Clone: CBYCL-385
Application*: E, IF, IP, WB
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (X155) (CBMAB-L2801-YJ)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: X155
Application*: IC, WB
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBYJL-1863) (CBMAB-L1846-YJ)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYJL-1863
Application*: WB, P
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBYJL-1862) (CBMAB-L1845-YJ)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1862
Application*: E, WB, P, IF, IC, F
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBYJL-1861) (CBMAB-L1844-YJ)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1861
Application*: WB
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (CBT2962) (V2LY-0625-LY502)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2962
Application*: WB, IH, IC, F
Datasheet SDS

Mouse Anti-LMNB2 Recombinant Antibody (A914) (CBMAB-AP11489LY)

Go to compareCompare
Target: LMNB2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A914
Application*: IHC, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry
Happy Thanksgiving
Happy Thanksgiving close ad