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NR1H3

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Anti-NR1H3 antibodies

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Cat Product Name Target Host Antibody Isotype Cross Reactivity Clone Application*
CBMAB-N0513-WJ Mouse Anti-NR1H3 Recombinant Antibody (4A4F7) NR1H3 Mouse IgG1 Human, rat 4A4F7 E, WB, IF
CBMAB-0751-YC Mouse Anti-NR1H3 Recombinant Antibody (1A1) NR1H3 Mouse IgG2c Human, Common fruit fly 1A1 IP, WB, M
CBMAB-N3358-WJ Mouse Anti-NR1H3 Recombinant Antibody (NR1HB11D6) NR1H3 Mouse IgG1 Human NR1HB11D6 DB
CBMAB-N3357-WJ Mouse Anti-NR1H3 Recombinant Antibody (1F5) NR1H3 Mouse IgG2b Human 1F5 WB
CBMAB-N3356-WJ Mouse Anti-NR1H3 Recombinant Antibody (1A5) NR1H3 Mouse IgG2a Human 1A5 WB, IH
CBMAB-N3355-WJ Mouse Anti-NR1H3 Recombinant Antibody (3E9) NR1H3 Mouse IgG2a, κ Human 3E9 E, WB
CBMAB-L0344-YJ Mouse Anti-NR1H3 Recombinant Antibody (PPZ0412) NR1H3 Mouse IgG2a Human PPZ0412 WB, IH, IP, GS
CBMAB-L0343-YJ Mouse Anti-NR1H3 Recombinant Antibody (K8607) NR1H3 Mouse IgG2a Human K8607 WB, IP, E, GS
CBMAB-L0341-YJ Mouse Anti-NR1H3 Recombinant Antibody (CBYJL-243) NR1H3 Mouse IgG2a Human CBYJL-243 WB, IH
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)