PGRMC2

PGRMC2 has ubiquitous expression in fat (RPKM 36.7), small intestine (RPKM 30.1) and 25 other tissues.
Full Name
Progesterone Receptor Membrane Component 2
Function
Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity).
May serve as a universal non-classical progesterone receptor in the uterus (Probable). Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus (By similarity).
Plays a role in adipocyte function and systemic glucose homeostasis (PubMed:28111073).
In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity).
Biological Process
Adipose tissue developmentManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Membrane
Nucleus envelope
Endoplasmic reticulum
Topology
Helical: 42-66
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Anti-PGRMC2 antibodies

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Mouse Anti-PGRMC2 Recombinant Antibody (CF337) (CBMAB-FT162LY)

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Target: PGRMC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF337
Application*: ELISA, WB
Datasheet SDS

Mouse Anti-PGRMC2 Recombinant Antibody (2A3) (CBMAB-A6610-LY)

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Target: PGRMC2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 2A3
Application*: WB, E
Datasheet SDS

Mouse Anti-PGRMC2 Recombinant Antibody (CBYC-P339) (CBMAB-P1633-YC)

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Target: PGRMC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P339
Application*: WB, P, F
Datasheet SDS

Mouse Anti-PGRMC2 Recombinant Antibody (CBYC-P338) (CBMAB-P1632-YC)

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Target: PGRMC2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYC-P338
Application*: E, P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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