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PRDM8

PRDM8 is a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm.

Anti-PRDM8 antibodies

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Mouse Anti-PRDM8 Recombinant Antibody (10F5) (CBMAB-0859-CN)

Target: PRDM8
Host: Mouse
Antibody Isotype: IgG2a
Cross Reactivity: Human
Clone: 10F5
Application*: E, M

Mouse Anti-PRDM8 Monoclonal Antibody (1A1) (CBMAB-0006-LY)

Target: PRDM8
Host: Mouse
Antibody Isotype: IgG2b
Cross Reactivity: Human
Clone: 1A1
Application*: IP, M

Mouse Anti-PRDM8 Recombinant Antibody (E-3) (CBMAB-P2722-YC)

Target: PRDM8
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Mouse, Rat, Human
Clone: E-3
Application*: WB, IP, IF, E
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)