TACC3

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011]
Full Name
TACC3 Gene(Protein Coding) Transforming Acidic Coiled-Coil Containing Protein 3
Function
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity).
Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825).
May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476).
Biological Process
Cell divisionIEA:UniProtKB-KW
Cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Cerebral cortex developmentManual Assertion Based On ExperimentIBA:GO_Central
Metaphase/anaphase transition of mitotic cell cycleManual Assertion Based On ExperimentIMP:UniProtKB
Microtubule cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Microtubule cytoskeleton organization involved in mitosisManual Assertion Based On ExperimentIMP:UniProtKB
Mitotic spindle organizationIEA:InterPro
Regulation of mitotic spindle organizationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton, spindle
Cytoplasm, cytoskeleton, spindle pole
In complex with CKAP5 localized to microtubule plus-ends in mitosis and interphase. In complex with CKAP5 and clathrin localized to inter-microtubule bridges in mitotic spindles.
View more

Anti-TACC3 antibodies

+ Filters
Loading...

Rabbit Anti-TACC3 Recombinant Antibody (CBYJT-1786) (CBMAB-T0848-YJ)

Go to compareCompare
Target: TACC3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Dog
Clone: CBYJT-1786
Application*: WB, IP, IF
Datasheet SDS

Rabbit Anti-TACC3 Recombinant Antibody (CBYJT-1785) (CBMAB-T0847-YJ)

Go to compareCompare
Target: TACC3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-1785
Application*: WB, P, IC, IF
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBYJT-1784) (CBMAB-T0846-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBYJT-1784
Application*: F, IC, IF, WB
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBYJT-1783) (CBMAB-T0845-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-1783
Application*: IF, WB
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (6F1) (CBMAB-T0844-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 6F1
Application*: F, IC, IF, IH, P, WB
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBYJT-1782) (CBMAB-T0843-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBYJT-1782
Application*: IC, IF, IH, P, WB
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBYJT-1781) (CBMAB-T0842-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1781
Application*: F, IC, IF, IH, P, WB
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBYJT-1780) (CBMAB-T0841-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1780
Application*: F, IC, IF, IH, P, WB
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBYJT-1779) (CBMAB-T0840-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1779
Application*: WB, IH, IF, F
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBYJT-1778) (CBMAB-T0839-YJ)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1778
Application*: F, IC, IF, IH, P, WB
Datasheet SDS

Mouse Anti-TACC3 (AA 1-101) Recombinant Antibody (CBFYE-1664) (CBMAB-E2333-FY)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBFYE-1664
Application*: E, P, WB
Datasheet SDS

Mouse Anti-TACC3 Recombinant Antibody (CBFYE-1663) (CBMAB-E2332-FY)

Go to compareCompare
Target: TACC3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-1663
Application*: F, IF, P, WB
Datasheet SDS

Rabbit Anti-TACC3 Recombinant Antibody (
10G7) (V2LY-0725-LY1235)

Go to compareCompare
Target: TACC3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 10G7
Application*: E, WB, IH
Datasheet SDS

Rabbit Anti-TACC3 Recombinant Antibody (D9E4) (CBMAB-CP2682-LY)

Go to compareCompare
Target: TACC3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Dog
Clone: D9E4
Application*: WB, IP, IF (IC)
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry
Happy Holidays
Happy Holidays close ad