Sign in or Register   Sign in or Register
  |  

Mouse Anti-ASGR2 Recombinant Antibody (1D7) (CBMAB-A0538-LY)

The product is antibody recognizes ASGR2. The antibody 1D7 immunoassay techniques such as: WB, ELISA.
See all ASGR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D7
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
ASGR2 (AAH17251, 1 a.a. ~ 287 a.a) full-length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
asialoglycoprotein receptor 2
Introduction
This cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. [provided by RefSeq]
Entrez Gene ID
433
UniProt ID
P07307
Alternative Names
ASGP-R; CLEC4H2; Hs.1259; L-H2
Function
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Biological Process
Bone mineralization Source: Ensembl
Cell surface receptor signaling pathway Source: ProtInc
Lipid homeostasis Source: Ensembl
Protein N-linked glycosylation via asparagine Source: Reactome
Regulation of protein stability Source: Ensembl
Viral process Source: UniProtKB-KW
Cellular Location
Membrane
Topology
Cytoplasmic: 1-58 aa
Helical: 59-79 aa
Extracellular: 80-311 aa
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ASGR2 Recombinant Antibody (1D7)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare