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Mouse Anti-CFTR Recombinant Antibody (CBYY-C1924) (CBMAB-C3362-YY)

This product is mouse antibody that recognizes CFTR. The antibody CBYY-C1924 can be used for immunoassay techniques such as: IF, IP, WB
See all CFTR antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYY-C1924
Antibody Isotype
IgG1
Application
IF, IP, WB

Basic Information

Immunogen
Recombinant protein encoding NBF1 domain of human CFTR. MW of Antigen: 165-170kD. Epitope: aa386-412. Cellular Localization: Cell membrane
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Buffer
0.2 mg/mL
Preservative
PBS, pH 7.4, 0.2% BSA, 40% glycerol
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cystic Fibrosis Transmembrane Conductance Regulator
Entrez Gene ID
Human1080
Mouse12638
Rat24255
UniProt ID
HumanQ20BH0
MouseP26361
RatP34158
Function
Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO3-; selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
Biological Process
Chloride transport Source: UniProtKB-KW
Cellular Location
Early endosome membrane; Endosome membrane; Recycling endosome membrane; Apical cell membrane; Cell membrane; Endoplasmic reticulum membrane; Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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