Sign in or Register   Sign in or Register
  |  

Mouse Anti-GCM1 Recombinant Antibody (3D2) (CBMAB-G2651-LY)

This product is antibody recognizes GCM1. The antibody 3D2 immunoassay techniques such as: ELISA, WB.
See all GCM1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3D2
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
GCM1 (NP_003634, 108 a.a. ~ 166 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: QQRKRCPNCD GPLKLIPCRG HGGFPVTNFW RHDGRFIFFQ SKGEHDHPKP ETKLEAEA*
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glial Cells Missing Homolog 1
Introduction
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008]
Entrez Gene ID
UniProt ID
Alternative Names
Glial Cells Missing Homolog 1; GCM Motif Protein 1; HGCMa; GCMA; Glial Cells Missing (Drosophila) Homolog A; Glial Cells Missing Homolog 1 (Drosophila); Chorion-Specific Transcription Factor GCMa;
Function
Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes (PubMed:10542267, PubMed:18160678).

Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer (PubMed:10542267).

Binds to the SYDE1 promoter (PubMed:27917469).

Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (PubMed:19219068).
Biological Process
Anatomical structure morphogenesis Source: ProtInc
Astrocyte fate commitment Source: Ensembl
Branching involved in labyrinthine layer morphogenesis Source: Ensembl
Cell differentiation involved in embryonic placenta development Source: GO_Central
Gliogenesis Source: GO_Central
Positive regulation of syncytium formation by plasma membrane fusion Source: Ensembl
Positive regulation of transcription, DNA-templated Source: MGI
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of cell differentiation involved in embryonic placenta development Source: UniProtKB
Regulation of transcription, DNA-templated Source: MGI
Regulation of transcription by RNA polymerase II Source: GO_Central
Transcription by RNA polymerase II Source: UniProtKB
Cellular Location
Nucleus
PTM
Polyubiquitinated in the presence of UBE2D2 and FBXW2 (in vitro).
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-GCM1 Recombinant Antibody (3D2)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare